Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside

Base Information

• Chemical Name: Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside
• CAS No.: 59981-27-0
• Molecular Formula: C₈H₁₆O₅
• Molecular Weight: 192.212
• Mol file: 59981-27-0.mol

Synonyms:Methyl 2-O-Methyl-α-D-fucopyranoside;Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside;Methyl 2-O-Methyl-a-D-fucopyranoside;Methyl 6-Deoxy-2-O-methyl-a-D-galactopyranoside

Chemical Property of Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside

Chemical Property:

• PSA: 68.15000
• LogP: -0.88560
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

98%Min ^*data from raw suppliers

Methyl 6-deoxy-2-O-methyl-a-D-galactopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside (cas# 59981-27-0) is a compound useful in organic synthesis.

Technology Process of Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside

There total 11 articles about Methyl 6-Deoxy-2-O-methyl-α-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + onjisaponin A octadeca-O-methyl ether monomethyl ester → methyl 2,3,4-tri-O-methyl-β-D-apio-D-furanoside (4098-05-9,32445-84-4,32453-30-8,32453-34-2) + Methyl-(6-desoxy-2-O-methyl-α-L-mannopyranosid) (14917-72-7,17013-99-9,29836-35-9,59981-27-0,71748-62-4,96896-34-3,99603-80-2,112457-11-1,124264-66-0,59013-63-7) + methyl 2,3,4,6-tetra-O-methyl-β-D-galactopyranoside (2296-47-1)

Guidance literature:

With hydrogenchloride; for 2h; Further byproducts given; Heating;

DOI:10.1248/cpb.30.810

Reference yield:

methyl-3,4-di-O-benzyl-α-L-rhamnopyranoside (69558-07-2) → Methyl-(6-desoxy-2-O-methyl-α-L-mannopyranosid) (14917-72-7,17013-99-9,29836-35-9,59981-27-0,71748-62-4,96896-34-3,99603-80-2,112457-11-1,124264-66-0,59013-63-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Ag₂O / dimethylformamide

2: 10percent Pd/C / ethanol

With silver(l) oxide; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(00)85687-6

Reference yield:

methanol (67-56-1) + L-Rhamnose (3615-41-6,478518-52-4) → methyl 6-deoxy-3-O-methyl-α-L-mannopyranoside (5158-60-1,7045-56-9,10503-93-2,35862-73-8,35862-74-9,42822-17-3,64023-54-7,64913-18-4,93451-16-2,108267-98-7,109959-25-3,59013-64-8) + Methyl-(6-desoxy-2-O-methyl-α-L-mannopyranosid) (14917-72-7,17013-99-9,29836-35-9,59981-27-0,71748-62-4,96896-34-3,99603-80-2,112457-11-1,124264-66-0,59013-63-7)

Guidance literature:

methanol; L-Rhamnose; With hydrogenchloride; at 70 ℃; for 24h;

With boric acid; diazomethyl-trimethyl-silane; In 1,4-dioxane; diethyl ether; at 20 ℃; for 5h;

DOI:10.1021/jo3008622

upstream raw materials:

methyl-(O³,O⁴-diacetyl-O²-methyl-ξ-L-rhamnopyranoside)

barium methoxide

methanol

methyl 4-O-benzyl-2-O-methyl-α-L-rhamnopyranoside

Downstream raw materials:

O²-methyl-6-deoxy-D-altrose

methyl 3-O-benzoyl-2-O-methyl-α-D-fucopyranoside

methyl 2,3-di-O-benzoyl-α-D-fucopyranoside

methyl 3-O-benzoyl-2,4-di-O-methyl-α-D-fucopyranoside