(1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-YL)methyl acetate

Base Information

Chemical Name:(1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-YL)methyl acetate
CAS No.:637318-19-5
Molecular Formula:C14H13F3N2O3
Molecular Weight:314.26
Hs Code.:
DSSTox Substance ID:DTXSID80464186
Wikidata:Q82289418
Mol file:637318-19-5.mol

Synonyms:637318-19-5;(1-(4-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-YL)METHYL ACETATE;DTXSID80464186;AB44711

Suppliers and Price of (1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-YL)methyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1-(4-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-YL)METHYL ACETATE 95.00%
5MG
$ 505.90

Total 2 raw suppliers

Chemical Property of (1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-YL)methyl acetate

Chemical Property:

PSA：53.35000
LogP:2.96280
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:314.08782677
Heavy Atom Count:22
Complexity:384

Purity/Quality:

98%min ^*data from raw suppliers

(1-(4-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-YL)METHYL ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC1=CC(=NN1C2=CC=C(C=C2)OC)C(F)(F)F

Technology Process of (1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-YL)methyl acetate

There total 4 articles about (1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-YL)methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127-08-2
potassium acetate

: 5-bromomethyl-1-(4-methoxy-phenyl)-3-trifluoromethyl-1H-pyrazole

: 637318-19-5
acetic acid 2-(4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-ylmethyl ester

Guidance literature:: With 18-crown-6 ether; In acetonitrile; at 20 ℃; for 18h;
DOI:10.1021/jm030212h

Reference yield:

: 367-57-7
1,1,1-Trifluoro-2,4-pentanedione

: 637318-19-5
acetic acid 2-(4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / AcOH / 2-methoxy-ethanol / 18 h / Heating

2: N-bromosuccinimide; benzoyl peroxide / CCl₄ / 18 h / Heating; irradiation

3: 18-crown-6 / acetonitrile / 18 h / 20 °C

With N-Bromosuccinimide; 18-crown-6 ether; acetic acid; dibenzoyl peroxide; In tetrachloromethane; 2-methoxy-ethanol; acetonitrile;
DOI:10.1021/jm030212h

Reference yield:

: 19501-58-7
4-methoxyphenylhydrazine hydrochloride

: 637318-19-5
acetic acid 2-(4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / AcOH / 2-methoxy-ethanol / 18 h / Heating

2: N-bromosuccinimide; benzoyl peroxide / CCl₄ / 18 h / Heating; irradiation

3: 18-crown-6 / acetonitrile / 18 h / 20 °C

With N-Bromosuccinimide; 18-crown-6 ether; acetic acid; dibenzoyl peroxide; In tetrachloromethane; 2-methoxy-ethanol; acetonitrile;
DOI:10.1021/jm030212h