1-Benzyl-3-methylene-piperidin-2-one

Base Information

Chemical Name:1-Benzyl-3-methylene-piperidin-2-one
CAS No.:50586-10-2
Molecular Formula:C13H15NO
Molecular Weight:201.268
Hs Code.:
DSSTox Substance ID:DTXSID90442733
Wikidata:Q82260185
Mol file:50586-10-2.mol

Synonyms:50586-10-2;1-BENZYL-3-METHYLENE-PIPERIDIN-2-ONE;DTXSID90442733

Suppliers and Price of 1-Benzyl-3-methylene-piperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-BENZYL-3-METHYLENE-PIPERIDIN-2-ONE 95.00%
5MG
$ 498.88

Total 2 raw suppliers

Chemical Property of 1-Benzyl-3-methylene-piperidin-2-one

Chemical Property:

PSA：20.31000
LogP:2.30310
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:201.115364102
Heavy Atom Count:15
Complexity:253

Purity/Quality:

99% ^*data from raw suppliers

1-BENZYL-3-METHYLENE-PIPERIDIN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C1CCCN(C1=O)CC2=CC=CC=C2

Technology Process of 1-Benzyl-3-methylene-piperidin-2-one

There total 14 articles about 1-Benzyl-3-methylene-piperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 201230-82-2
carbon monoxide

: 157286-98-1
N-benzyl-4-<(trifluoromethanesulfonyl)oxy>-4-pentenylamine

: 50586-10-2
1-Benzyl-3-methylenepiperidin-2-one

Guidance literature:: With tributyl-amine; Pd(PPh₃); In acetonitrile; at 65 ℃; for 15h; under 760 Torr;
DOI:10.1016/0040-4020(95)00219-X

Reference yield: 70.0%

: 72551-53-2
ethyl 1-benzylpiperidine-3-carboxylate

: 50586-10-2
1-Benzyl-3-methylenepiperidin-2-one

Guidance literature:: ethyl 1-benzylpiperidine-3-carboxylate; With sodium hydroxide; In methanol; water; at 20 ℃; for 12h; Inert atmosphere;

With triethylamine; In acetic anhydride; at 90 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.joc.6b02207

Reference yield: 61.0%

: 201230-82-2
carbon monoxide

: 86953-49-3
N-benzyl-4-bromo-4-pentenylamine

: 50586-10-2
1-Benzyl-3-methylenepiperidin-2-one

Guidance literature:: With tributyl-amine; triphenylphosphine; palladium diacetate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 100 ℃; for 5h;
DOI:10.1021/jo00170a037