O-Phospho-DL-tyrosine

Base Information

Chemical Name:O-Phospho-DL-tyrosine
CAS No.:41863-47-2
Molecular Formula:C9H12NO6P
Molecular Weight:261.171
Hs Code.:2931900090
ChEMBL ID:CHEMBL310565
DSSTox Substance ID:DTXSID50404615,DTXSID00865015
Nikkaji Number:J1.681.592F
Wikidata:Q27145036
Mol file:41863-47-2.mol

Synonyms:41863-47-2;O-PHOSPHO-DL-TYROSINE;O(4)-phosphotyrosine;O-phosphonotyrosine;O-PHOSPHO-DL-TYROSINE);H-Tyr(POH)-OH;CHEMBL310565;CHEBI:74956;2-Amino-3-(4-phosphonooxy-phenyl)-propionic acid;2-amino-3-(4-phosphonooxyphenyl)propanoic acid;4-(phosphonooxy)phenylalanine;2-Amino-3-(4-(phosphonooxy)phenyl)propanoic acid;SCHEMBL273663;DTXSID00865015;DTXSID50404615;BDBM50080265;FT-0673871;Q27145036

Suppliers and Price of O-Phospho-DL-tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-AMINO-3-[4-(OXYPHOSPHINYLOXYPHOSPHINYL)PHENYL]PROPANOIC ACID 95.00%
5MG
$ 502.56

Total 1 raw suppliers

Chemical Property of O-Phospho-DL-tyrosine

Chemical Property:

Vapor Pressure:9.05E-15mmHg at 25°C
Refractive Index:1.635
Boiling Point:590.1°C at 760 mmHg
Flash Point:310.7°C
PSA：139.89000
Density:1.63g/cm³
LogP:0.81280
Storage Temp.:?20°C
XLogP3:-2.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:261.04022410
Heavy Atom Count:17
Complexity:309

Purity/Quality:

98% ^*data from raw suppliers

2-AMINO-3-[4-(OXYPHOSPHINYLOXYPHOSPHINYL)PHENYL]PROPANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)N)OP(=O)(O)O

Technology Process of O-Phospho-DL-tyrosine

There total 3 articles about O-Phospho-DL-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 2-tert-butoxycarbonylamino-3-[4-(diethoxy-phosphoryloxy)-phenyl]-propionic acid methyl ester

: 41863-47-2
(S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic-acid

Guidance literature:: With hydrogenchloride; In water; for 10h; Heating;
DOI:10.1002/(SICI)1526-4998(200004)56:4<368::AID-PS153>3.0.CO;2-V

Reference yield:

: methyl 3-(4-((trifluoromethyl)sulfonyloxy)phenyl)-2-((tert-butoxy)carbonylamino)propionate

: 41863-47-2
(S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic-acid

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / triethylamine / tetrakis(triphenylphosphine)palladium / toluene / 24 h / 90 °C

2: 70 percent / aq. HCl / H₂O / 10 h / Heating

With hydrogenchloride; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; toluene; 1: Substitution / 2: Hydrolysis;
DOI:10.1002/(SICI)1526-4998(200004)56:4<368::AID-PS153>3.0.CO;2-V

Reference yield:

: 188576-13-8
methyl 2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate

: 41863-47-2
(S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic-acid

Guidance literature:: Multi-step reaction with 3 steps

1: 280 mg / pyridine

2: 85 percent / triethylamine / tetrakis(triphenylphosphine)palladium / toluene / 24 h / 90 °C

3: 70 percent / aq. HCl / H₂O / 10 h / Heating

With pyridine; hydrogenchloride; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; toluene; 1: Substitution / 2: Substitution / 3: Hydrolysis;
DOI:10.1002/(SICI)1526-4998(200004)56:4<368::AID-PS153>3.0.CO;2-V