Methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate

Base Information

Chemical Name:Methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate
CAS No.:188576-13-8
Molecular Formula:C15H21NO5
Molecular Weight:295.335
Hs Code.:
European Community (EC) Number:819-333-5
DSSTox Substance ID:DTXSID201347386
Nikkaji Number:J1.868.983I

Synonyms:methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate;188576-13-8;methyl 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate;N-boc-d-tyrosine methyl ester;SCHEMBL539575;Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate;Boc-D-Tyr-OMe;(R)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate;NQIFXJSLCUJHBB-UHFFFAOYSA-N;DTXSID201347386;AKOS005216873;AKOS032947436;SB44185;SY003952;SY030159;AM20040467;FT-0602675;FT-0629764;EN300-53583;A826233;A865423;Methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}tyrosinate;Z802638334;methyl-2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate;Methyl2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate;2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid methyl ester;2-tert-butoxycarbonylamino-3-(4-hydroxyphenyl)propionic acid methyl ester;methyl (2S)-2-(tert-butoxycarbonylamino)-3-(4-hydroxyphenyl)propanoate;Boc-Tyr-OMe;BOC-D-TYROSINE METHYL ESTER;BOC-D-TYROSINE-OME;N-T-BUTOXYCARBONYL-D-TYROSINE METHYL ESTER;N-T-boc-D-tyrosine methyl ester;(R)-Methyl 2-((tert-butoxycarbonyl)aMino)-3-(4-hydroxyphenyl)propanoate

Suppliers and Price of Methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:295.14197277
Heavy Atom Count:21
Complexity:356

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)O)C(=O)OC

Technology Process of Methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate

There total 9 articles about Methyl 2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 188576-13-8
methyl 2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate

Guidance literature:: With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 2h;

Reference yield: 99.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 142847-18-5
N-(tert-butoxycarbonyl)tyrosine

: 188576-13-8
methyl 2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 0.5h;
DOI:10.1039/c001894e

Reference yield: 98.0%

: methyl 3-(4-(allyloxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoate

: 188576-13-8
methyl 2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate

Guidance literature:: methyl 3-(4-(allyloxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoate; With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; diphenylsilane; 4,4'-di-tert-butyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 20 ℃; for 8h; Schlenk technique; Inert atmosphere; Sealed tube;

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 50 ℃; for 2h; Reagent/catalyst; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1016/j.tetlet.2021.153341