5(4H)-Oxazolone, 2-(3-methoxy-2-methylphenyl)-4-methyl-4-(1-methylethyl)-

Base Information

• Chemical Name: 5(4H)-Oxazolone, 2-(3-methoxy-2-methylphenyl)-4-methyl-4-(1-methylethyl)-
• CAS No.: 551964-00-2
• Molecular Formula: C15H19NO3
• Molecular Weight: 261.32
• Hs Code.: 2934999090
• Mol file: 551964-00-2.mol

Synonyms:5(4H)-Oxazolone, 2-(3-methoxy-2-methylphenyl)-4-methyl-4-(1-methylethyl)-

Chemical Property of 5(4H)-Oxazolone, 2-(3-methoxy-2-methylphenyl)-4-methyl-4-(1-methylethyl)-

Chemical Property:

• PSA: 47.89000
• LogP: 2.15730

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5(4H)-Oxazolone, 2-(3-methoxy-2-methylphenyl)-4-methyl-4-(1-methylethyl)-

There total 1 articles about 5(4H)-Oxazolone, 2-(3-methoxy-2-methylphenyl)-4-methyl-4-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-2-amino-2,3-dimethylbutyric acid (26287-62-7) + 3-methoxy-2-methylbenzoyl chloride (24487-91-0) → 4-isopropyl-2-(3-methoxy-2-methyl-phenyl)-4-methyl-4H-oxazol-5-one (551964-00-2)

Guidance literature:

With pyridine; at 20 ℃; for 168000h;

DOI:10.1016/S0960-894X(02)00980-0

Reference yield: 69.0%

4-isopropyl-2-(3-methoxy-2-methyl-phenyl)-4-methyl-4H-oxazol-5-one (551964-00-2) → N-(1-hydroxymethyl-1,2-dimethyl-propyl)-3-methoxy-2-methyl-benzamide (551964-07-9)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 16h;

DOI:10.1016/S0960-894X(02)00980-0

Reference yield:

N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) + 4-isopropyl-2-(3-methoxy-2-methyl-phenyl)-4-methyl-4H-oxazol-5-one (551964-00-2) → 3-methoxy-N-[1-(methoxy-methyl-carbamoyl)-1,2-dimethyl-propyl]-2-methyl-benzamide (551964-03-5)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃;

DOI:10.1016/S0960-894X(02)00980-0

upstream raw materials:

L-2-amino-2,3-dimethylbutyric acid

3-methoxy-2-methylbenzoyl chloride

Downstream raw materials:

3-methoxy-N-[1-(methoxy-methyl-carbamoyl)-1,2-dimethyl-propyl]-2-methyl-benzamide

N-(1-hydroxymethyl-1,2-dimethyl-propyl)-3-methoxy-2-methyl-benzamide

N-(1-formyl-1,2-dimethyl-propyl)-3-methoxv-2-methyl-benzamide

N-[1-(hydroxy-m-tolyl-methyl)-1,2-dimethyl-propyl]-3-methoxy-2-methyl-benzamide