1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester

Base Information

• Chemical Name: 1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester
• CAS No.: 55887-55-3
• Molecular Formula: C17H27NO3Si2
• Molecular Weight: 349.57
• Mol file: 55887-55-3.mol

Synonyms:1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester

Chemical Property of 1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester

Chemical Property:

• PSA: 40.46000
• LogP: 4.25350

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester

There total 2 articles about 1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methoxy-1H-indole-3-acetic acid (3471-31-6,142396-09-6) + N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide (24589-78-4) → N,O-Bis(trimethylsilyl)-5-methoxyindolyl-3-essigsaeureester (55887-55-3)

Guidance literature:

Reference yield:

→ N,O-Bis(trimethylsilyl)-5-methoxyindolyl-3-essigsaeureester (55887-55-3)

Guidance literature:

5-Methoxyindol-3-essigsaeure-d4, Bis(trimethylsilyl)trifluoracetamid;

DOI:10.1002/jlcr.2580140404

Reference yield:

1-Chloro-4-(chloromethyl)benzene (104-83-6) + N,O-Bis(trimethylsilyl)-5-methoxyindolyl-3-essigsaeureester (55887-55-3) → N-(4-Chlorbenzyl)-5-methoxy-indolyl-3-essigsaeure (3446-79-5)

Guidance literature:

at 80 ℃;

upstream raw materials:

5-methoxy-1H-indole-3-acetic acid

N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide

Downstream raw materials:

N-(4-Chlorbenzyl)-5-methoxy-indolyl-3-essigsaeure

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