5-(Methoxycarbonyl)nicotinic acid

Base Information

• Chemical Name: 5-(Methoxycarbonyl)nicotinic acid
• CAS No.: 5027-65-6
• Molecular Formula: C8H7NO4
• Molecular Weight: 181.148
• Hs Code.: 2933399090
• European Community (EC) Number: 834-556-8
• DSSTox Substance ID: DTXSID80600966
• Nikkaji Number: J1.385.301K
• Wikidata: Q82497318
• Mol file: 5027-65-6.mol

Synonyms:5-(methoxycarbonyl)nicotinic acid;5027-65-6;3,5-Pyridinecarboxylic acid, 3-methyl ester;5-(methoxycarbonyl)pyridine-3-carboxylic acid;5-methoxycarbonylpyridine-3-carboxylic acid;MFCD07367955;PYRIDINE-3,5-DICARBOXYLIC ACID MONOMETHYL ESTER;SCHEMBL56952;5-(methoxycarbonyl)nicotinicacid;DTXSID80600966;GUXKBDHITFXEJG-UHFFFAOYSA-N;AKOS015949347;AB31493;CS-W001581;AC-14314;AS-42957;SY105163;3,5-Pyridinecarboxylic acid,3-methyl ester;pyridine-3,5-dicarboxylic acid methyl ester;EN300-44992;J-516360;Z451334748

Chemical Property of 5-(Methoxycarbonyl)nicotinic acid

Chemical Property:

• Vapor Pressure: 1.09E-05mmHg at 25°C
• Refractive Index: 1.56
• Boiling Point: 356.1°Cat760mmHg
• Flash Point: 169.2°C
• PSA: 76.49000
• Density: 1.361g/cm³
• LogP: 0.56640
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 181.03750770
• Heavy Atom Count: 13
• Complexity: 216

Purity/Quality:

97% ^*data from raw suppliers

5-(Methoxycarbonyl)nicotinicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CN=CC(=C1)C(=O)O

Technology Process of 5-(Methoxycarbonyl)nicotinic acid

There total 4 articles about 5-(Methoxycarbonyl)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

dimethyl pyridine-3,5-dicarboxylate (4591-55-3) → pyridine-3,5-dicarboxylic acid monomethyl ester (5027-65-6)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 12h;

DOI:10.1021/ja0016708

Reference yield: 46.0%

methanol (67-56-1) + 3,5-Pyridinedicarboxylic acid (499-81-0) → pyridine-3,5-dicarboxylic acid monomethyl ester (5027-65-6)

Guidance literature:

methanol; 3,5-Pyridinedicarboxylic acid; With thionyl chloride; at 0 - 50 ℃;

With potassium hydrogencarbonate; In methanol; water; at 20 ℃;

With hydrogenchloride; In methanol; water; pH=3;

Reference yield:

dimethyl pyridine-3,5-dicarboxylate (4591-55-3) → 3,5-Pyridinedicarboxylic acid (499-81-0) + pyridine-3,5-dicarboxylic acid monomethyl ester (5027-65-6)

Guidance literature:

dimethyl pyridine-3,5-dicarboxylate; With sodium hydroxide; In methanol; at 20 ℃; for 0.25h;

In water; pH=2; Acidic conditions;

upstream raw materials:

dimethyl pyridine-3,5-dicarboxylate

methanol

3,5-Pyridinedicarboxylic acid

Downstream raw materials:

5-carbamoylpyridine-3-carboxylic acid

5-[4-(4-Formyl-benzyloxy)-2-hydroxy-3-propyl-benzoyl]-nicotinic acid

C₂₁H₂₄N₂O₆

C₄₄H₅₁N₅O₁₀

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 5027-65-6 3,5-PYRIDINECARBOXYLIC ACID, 3-METHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send