2,3-Dichlorosulfanilic acid

Base Information

• Chemical Name: 2,3-Dichlorosulfanilic acid
• CAS No.: 56978-58-6
• Molecular Formula: C6H5Cl2NO3S
• Molecular Weight: 0
• Mol file: 56978-58-6.mol

Synonyms:2,3-Dichlorosulfanilic acid

Chemical Property of 2,3-Dichlorosulfanilic acid

Chemical Property:

• PSA: 88.77000
• LogP: 3.48430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Dichlorosulfanilic acid

There total 4 articles about 2,3-Dichlorosulfanilic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

2,3-dichloro-4-nitrobenzenesulphonic acid (105565-53-5) → 4-Amino-2,3-dichloro-benzenesulfonic acid (56978-58-6)

Guidance literature:

With iron; iron(II) sulfate; In water; at 90 - 95 ℃; for 5h;

DOI:10.1039/P29860001107

Reference yield:

2,3-dichloroformanilide (6327-47-5) → 4-Amino-2,3-dichloro-benzenesulfonic acid (56978-58-6)

Guidance literature:

Multi-step reaction with 4 steps

2: 1.) hydrochloric acid; 2.) sodium nitrite / 1.) water, 2h, 30-40 deg C; 2.) water, >5 deg C, 1h

3: 1.) sodium sulphite, hydrochloric acid, copper sulphate 2.) sodium hydroxide / 1.) water, >5 deg C, 1h; 2.) water, room temperature, 18h

4: 56 percent / Iron powder, ferrous sulphate / H₂O / 5 h / 90 - 95 °C

With hydrogenchloride; sodium hydroxide; copper(I) sulfate; iron; iron(II) sulfate; sodium sulfite; sodium nitrite; In water;

DOI:10.1039/P29860001107

Reference yield:

2,3-dichloro-4-nitroaniline (69951-03-7) → 4-Amino-2,3-dichloro-benzenesulfonic acid (56978-58-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) hydrochloric acid; 2.) sodium nitrite / 1.) water, 2h, 30-40 deg C; 2.) water, >5 deg C, 1h

2: 1.) sodium sulphite, hydrochloric acid, copper sulphate 2.) sodium hydroxide / 1.) water, >5 deg C, 1h; 2.) water, room temperature, 18h

3: 56 percent / Iron powder, ferrous sulphate / H₂O / 5 h / 90 - 95 °C

With hydrogenchloride; sodium hydroxide; copper(I) sulfate; iron; iron(II) sulfate; sodium sulfite; sodium nitrite; In water;

DOI:10.1039/P29860001107

upstream raw materials:

2,3-dichloro-4-nitrobenzenesulphonic acid

2,3-dichloro-4-nitroaniline

2,3-dichloroformanilide

Downstream raw materials:

4-(2-Acetylamino-4-diethylamino-phenylazo)-2,3-dichloro-benzenesulfonic acid

4-(4-Amino-2-diethylamino-6-methyl-pyrimidin-5-ylazo)-2,3-dichloro-benzenesulfonic acid

2,3-Dichloro-4-(4,6-diamino-2-ethylsulfanyl-pyrimidin-5-ylazo)-benzenesulfonic acid

4-(5-Amino-3-methyl-1-phenyl-1H-pyrazol-4-ylazo)-2,3-dichloro-benzenesulfonic acid

Refernces