69951-03-7

Basic information

• Product Name: BENZENAMINE, 2,3-DICHLORO-4-NITRO-
• Synonyms: BENZENAMINE, 2,3-DICHLORO-4-NITRO-;2-Fluoro-3-methoxyphenylboronicacidBrassfoil
• CAS NO: 69951-03-7
• Molecular Formula: C₆H₄Cl₂N₂O₂
• Molecular Weight: 207.01
• Mol File: 69951-03-7.mol

Chemical Properties

• Boiling Point: 367.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.624±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -2.10±0.14(Predicted)
• CAS DataBase Reference: BENZENAMINE, 2,3-DICHLORO-4-NITRO-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZENAMINE, 2,3-DICHLORO-4-NITRO-(69951-03-7)
• EPA Substance Registry System: BENZENAMINE, 2,3-DICHLORO-4-NITRO-(69951-03-7)

Safety Data

• Hazardous Substances Data: 69951-03-7(Hazardous Substances Data)

Usage

Uses

Used in Dye and Pigment Industry:
Benzenamine, 2,3-dichloro-4-nitrois used as a chemical intermediate in the synthesis of dyes and pigments. Its unique chemical structure allows for the creation of a wide range of colors and properties, making it valuable in the production of various types of dyes and pigments for different applications.
Used in Pharmaceutical Industry:
Benzenamine, 2,3-dichloro-4-nitrois also utilized as a building block in the development of pharmaceuticals. Its chemical properties enable the synthesis of various drug compounds, contributing to the advancement of new medications and therapies.
However, due to its toxic nature and potential carcinogenic effects, the use of Benzenamine, 2,3-dichloro-4-nitroin these industries must be carefully managed and controlled to minimize exposure and environmental impact. Proper safety measures, including the use of personal protective equipment and adherence to regulatory guidelines, are essential when working with this substance.

Upstream product

• 6327-47-5 2,3-dichloroformanilide 
• 23068-36-2 N-(2,3-dichlorophenyl)-acetamide 
• 608-27-5 2,3-dichloroaniline 
• 261764-91-4 2,3-dichloro-4-nitroacetanilide 
• 69951-04-8 N-(2,3-dichlorophenyl)-4-methylbenzenesulfonamide 

Downstream Products

• 24311-36-2 2-chloro-5-methoxy-4-nitro-aniline 
• 97203-10-6 2,3-dichloro-N,N-dimethyl-4-nitroaniline 
• 69950-98-7 C₁₇H₂₉ClN₄O₇P₂S₂ 
• 105548-26-3 4-(2-Acetylamino-4-diethylamino-phenylazo)-2,3-dichloro-benzenesulfonic acid 
• 105547-88-4 4-(4-Amino-2-diethylamino-6-methyl-pyrimidin-5-ylazo)-2,3-dichloro-benzenesulfonic acid 
• 105548-07-0 2,3-Dichloro-4-(4,6-diamino-2-ethylsulfanyl-pyrimidin-5-ylazo)-benzenesulfonic acid 
• 105547-67-9 4-(5-Amino-3-methyl-1-phenyl-1H-pyrazol-4-ylazo)-2,3-dichloro-benzenesulfonic acid 
• 105565-53-5 2,3-dichloro-4-nitrobenzenesulphonic acid 

Relevant articles and documents

Design, synthesis, and preliminary in vitro and in silico antiviral activity of [4,7]phenantrolines and 1-oxo-1,4-dihydro-[4,7]phenantrolines against single-stranded positive-sense RNA genome viruses

Following the antiviral screening of a wide series of new angular and linear N-tricyclic systems both in silico and in vitro, the [4,7]phenantroline nucleus emerged as a new ring system endowed with activity against viruses containing single-stranded, positive-sense RNA genomes (ssRNA+). Here, we report our new pathway to the synthesis of this nucleus and of several related derivatives, as well as the results of both cell-based antiviral assays and molecular dynamics simulations. In the antiviral screening, several compounds (9 and 16-20) showed to be fairly active against BVDV, CVB-2, and Polio 1 (EC50, 6-25 μM). According to molecular dynamics simulations, compounds (15) and (17) emerged for its potency against the HCV NS5B, with a calculated IC50 of 11-12 μM.

Synthesis of two novel tricyclic rings: Triazolo[4,5-g]- quinolines and pyrido[2,3-g]quinoxalines derived from 6,7-diaminoquinolines

A general simple route for the synthesis of triazolo[4,5-g]quinolines and pyrido[2,3-g]quinoxalines is described. The heterocycles obtained were fully characterised by their spectroscopical properties. A revision of the nitration of the 2,3-dichloroacetanilide is also discussed, since it afforded the request nitro derivative to build up the key intermediate 6,7- diaminoquinolines.

The Influence of Chlorine and Sulphonate Substituents on the Visible Absorption Maxima of Some Azo Dyes

A total of 110 arylazo dyes have been prepared, based on five benzenoid and heterocyclic coupling components, and containing combinations of chlorine and sulphonate (sulpho) substituents in the diazo components.Their visible absorption maxima have been analysed in order to determine the degree to which chloro and sulfo substituent influences are constant and transferable, both within a series, and between series.Additivity is found to pertain, if allowances are made for steric effects.A 2-sulpho group alone can induce nonplanarity, depending on the nature of the coupling component.The 2-sulpho-3-chloro combination is particularly responsible for hypsochromic shifts unexpected on the basis of strict additivity.Computer-aided molecular modelling studies have clarified the steric interactions present.Di-ortho-substitution also induces nonplanarity and hypsochromic effects.There is some evidence for non-equivalence of a substituent in the two distinct meta-orientations, although MO calculations do not reproduce this behaviour.

P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents

There are provided substituted p-phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters, a method for the preparation of said esters and unsubstituted derivatives thereof and a method for controlling helminths in warm-blooded animals by administering to said animals an anthelmintically effective amount of said unsubstituted or substituted p-phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid ester.

Method for the control of cattle grubs employing a phenylene bis[imino(thio]carbonyl)diphosphor(thio)-amidic acid ester

There is provided a method for controlling the larvae of heel flies which parasitize ruminants and other warm-blooded animals by administering to said animals an effective amount of an unsubstituted or substituted phenylene bis[imino(thio)carbonyl]diphosp