4-Methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

Base Information

Chemical Name:4-Methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid
CAS No.:57367-54-1
Molecular Formula:C23H21O4P
Molecular Weight:392.391
Hs Code.:
DSSTox Substance ID:DTXSID70438755
Nikkaji Number:J1.802.598A
Mol file:57367-54-1.mol

Synonyms:57367-54-1;4-methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid;4-METHOXY-4-OXO-3-(TRIPHENYLPHOSPHORANYLIDENE)-BUTANOIC ACID;SCHEMBL1915303;DTXSID70438755;HNMTZWXMFCUEMQ-UHFFFAOYSA-N;2-(Triphenylphosphoranylidene)succinic acid 1-methyl ester;Butanedioic acid, (triphenylphosphoranylidene)-, 1-methyl ester

Suppliers and Price of 4-Methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

Chemical Property:

Boiling Point:574.5±52.0 °C(Predicted)
PSA：73.41000
Density:1.26±0.1 g/cm3(Predicted)
LogP:2.80060
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:392.11774614
Heavy Atom Count:28
Complexity:541

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CC(=O)O

Technology Process of 4-Methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

There total 3 articles about 4-Methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 906-65-0
3-(triphenyl-λ-phosphanylidene)dihydrofuran-2,5-dione

: 57367-54-1
4-methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

Guidance literature:: at 20 ℃; for 16h;
DOI:10.1002/asia.202000092

Reference yield:

: 603-35-0
triphenylphosphine

: 57367-54-1
4-methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetone / 40 °C / Inert atmosphere

2: 20 °C

In acetone;
DOI:10.1016/j.tetlet.2013.03.022

Reference yield:

: 603-35-0
triphenylphosphine

: 57367-54-1
4-methoxy-4-oxo-3-(triphenylphosphoranylidene)butanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / acetone

2: 75 percent / 24 h

In acetone;
DOI:10.1021/jm00062a009