1H-Imidazol-2-amine hydrochloride

Base Information

• Chemical Name: 1H-Imidazol-2-amine hydrochloride
• CAS No.: 57575-96-9
• Molecular Formula: C₃H₅N₃*ClH
• Molecular Weight: 119.554
• Hs Code.: 2933290090
• DSSTox Substance ID: DTXSID50480651
• Mol file: 57575-96-9.mol

Synonyms:1H-Imidazol-2-amine hydrochloride;57575-96-9;2-Amino-1H-imidazole hydrochloride;1H-imidazol-2-amine;hydrochloride;1H-Imidazol-2-amine xhydrochloride;2-AMINO-1H-IMIDAZOLE, HCL;1h-imidazole-2-amine;2-Amino-1h-imidazole HCl;52737-40-3;1H-Imidazol-2-amine, hydrochloride;imidazol-2-amine hydrochloride;2-aminoimidazole hydro-chloride;SCHEMBL4445175;DTXSID50480651;QKUZBZFCWCJPFK-UHFFFAOYSA-N;MFCD06795693;2-AMINOIMIDAZOLE HYDROCHLORIDE;AKOS015995645;AB29274;BS-28943

Chemical Property of 1H-Imidazol-2-amine hydrochloride

Chemical Property:

• Vapor Pressure: 0.000357mmHg at 25°C
• Refractive Index: ">
• Boiling Point: 313.8°Cat760mmHg
• Flash Point: 143.6°C
• PSA: 54.70000
• Density: g/cm³
• LogP: 1.37510
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 119.0250249
• Heavy Atom Count: 7
• Complexity: 45.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Amino-1H-imidazolehydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(N1)N.Cl

Technology Process of 1H-Imidazol-2-amine hydrochloride

There total 1 articles about 1H-Imidazol-2-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-amino-1H-imidazole hydrochloride (52737-40-3,57575-96-9)

Guidance literature:

2-(p-Brom-phenylazo)-imidazol (III), SnCl2/HCl;

Reference yield:

diethyl (2-chloro-6-fluoro-phenyl)-malonate (190521-88-1) + 2-amino-1H-imidazole hydrochloride (52737-40-3,57575-96-9) → 5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt (615269-36-8)

Guidance literature:

With DBN; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 4h;

Reference yield:

ethyl 2-(2-chloro-6-fluorophenyl)acetoacetate + 2-amino-1H-imidazole hydrochloride (52737-40-3,57575-96-9) → 5-hydroxy-6-(2-chloro-6-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine

Guidance literature:

With DBN; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 14h;

Downstream raw materials:

2-acetamidoimidazole

2-(2',4'-dimethoxy)phenyl-1H-imidazo<1,2-a>imidazole

1-(2,4-Dimethoxybenzoylmethyl)-6-(2,4-dimethoxyphenyl)-1H-imidazo<1,2-a>imidazole

5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt

Refernces