2-(1,4-Diazepan-1-yl)ethan-1-ol

Base Information

• Chemical Name: 2-(1,4-Diazepan-1-yl)ethan-1-ol
• CAS No.: 53427-65-9
• Molecular Formula: C7H16N2O
• Molecular Weight: 144.217
• Hs Code.: 2933990090
• European Community (EC) Number: 690-011-2
• DSSTox Substance ID: DTXSID10371435
• Wikidata: Q82158767
• Mol file: 53427-65-9.mol

Synonyms:1-(2-Hydroxyethyl)homopiperazine;1H-1,4-Diazepine-1-ethanol, hexahydro-;

Chemical Property of 2-(1,4-Diazepan-1-yl)ethan-1-ol

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.469
• Boiling Point: 257.239 °C at 760 mmHg
• PKA: 14.98±0.10(Predicted)
• Flash Point: 109.374 °C
• PSA: 35.50000
• Density: 0.985g/cm³
• LogP: -0.45930
• Storage Temp.: 2-8°C
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 144.126263138
• Heavy Atom Count: 10
• Complexity: 87.7

Purity/Quality:

98%min ^*data from raw suppliers

2-(1,4-Diazepan-1-yl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCCN(C1)CCO

Technology Process of 2-(1,4-Diazepan-1-yl)ethan-1-ol

There total 4 articles about 2-(1,4-Diazepan-1-yl)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-Diazacycloheptane (505-66-8) + iodoethyl alcohol → 2-(1,4-diazepan-1-yl)ethanol (53427-65-9)

Guidance literature:

In tetrahydrofuran;

Reference yield:

N,N'-Di(phenylsulphonyl)hexahydro-1,4-diazepin (5451-44-5) → 2-(1,4-diazepan-1-yl)ethanol (53427-65-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous H₂SO₄

2: aqueous methanol

With methanol; sulfuric acid;

DOI:10.1021/ja01633a057

Reference yield:

oxirane (75-21-8,99932-75-9) + 1,4-Diazacycloheptane (505-66-8) → 2-(1,4-diazepan-1-yl)ethanol (53427-65-9)

Guidance literature:

With methanol;

DOI:10.1021/ja01633a057

upstream raw materials:

oxirane

1,4-Diazacycloheptane

N,N'-Di(phenylsulphonyl)hexahydro-1,4-diazepin

Downstream raw materials:

1,5-diaza-bicyclo[3.2.2]nonane

N-cyclopropyl-3-(2-(cyclopropylmethyl)-4-((4-(2-hydroxyethyl)-1,4-diazepan-1-yl)methyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)-5-fluoro-4-methylbenzamide

4-((6-(5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-2-(cyclopropylmethyl)-1-oxo-1,2-dihydroisoquinolin-4-yl)methyl)-1-(2-hydroxyethyl)-1,4-diazepane 1-oxide

2-[4-(4-nitrophenyl)-[1,4]diazepan-1-yl]ethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 53427-65-9 2-(1,4-Diazepan-1-yl)ethan-1-ol

Send

Send

Metric Ton KG G Pound L ML

Send

Send