4-(4-Methoxybenzyl)-3-thiosemicarbazide

Base Information

Chemical Name:4-(4-Methoxybenzyl)-3-thiosemicarbazide
CAS No.:16735-76-5
Molecular Formula:C9H13 N3 O S
Molecular Weight:211.288
Hs Code.:2930909090
European Community (EC) Number:674-160-0
DSSTox Substance ID:DTXSID60351868
Wikidata:Q82128663
Mol file:16735-76-5.mol

Synonyms:4-(4-Methoxybenzyl)-3-thiosemicarbazide;16735-76-5;1-amino-3-[(4-methoxyphenyl)methyl]thiourea;n-(4-methoxybenzyl)hydrazinecarbothioamide;3-amino-1-[(4-methoxyphenyl)methyl]thiourea;Hydrazinecarbothioamide, N-[(4-methoxyphenyl)methyl]-;Maybridge4_003693;SCHEMBL6211890;DTXSID60351868;RJYHJXVBSQAYNL-UHFFFAOYSA-N;HMS1531H19;4-(p-methoxybenzyl)thiosemicarbazide;MFCD00060591;STL370591;4-(p-methoxybenzyl)-thiosemicarbazide;AKOS001073013;4-(p-methoxybenzyl)- thiosemicarbazide;CS-0219380;FT-0682093;EN300-03857;A810857;SR-01000039500;SR-01000039500-1;BRD-K37036284-001-01-1;BRD-K37036284-001-02-9;Z56886497

Suppliers and Price of 4-(4-Methoxybenzyl)-3-thiosemicarbazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Methoxybenzyl)-3-thiosemicarbazide
50mg
$ 45.00

SynQuest Laboratories
4-(4-Methoxybenzyl)-3-thiosemicarbazide
250 mg
$ 42.00

SynQuest Laboratories
4-(4-Methoxybenzyl)-3-thiosemicarbazide
1 g
$ 61.00

Matrix Scientific
4-(4-Methoxybenzyl)-3-thiosemicarbazide
1g
$ 64.00

Matrix Scientific
4-(4-Methoxybenzyl)-3-thiosemicarbazide
5g
$ 193.00

Crysdot
4-(4-Methoxybenzyl)-3-thiosemicarbazide 95+%
25g
$ 535.00

American Custom Chemicals Corporation
4-(4-METHOXYBENZYL)-3-THIOSEMICARBAZIDE 95.00%
1G
$ 652.58

Alichem
4-(4-Methoxybenzyl)-3-thiosemicarbazide
25g
$ 594.00

AK Scientific
4-(4-Methoxybenzyl)-3-thiosemicarbazide
5g
$ 174.00

Total 10 raw suppliers

Chemical Property of 4-(4-Methoxybenzyl)-3-thiosemicarbazide

Chemical Property:

Vapor Pressure:0.000226mmHg at 25°C
Melting Point:131-133°C
Boiling Point:362.5°Cat760mmHg
Flash Point:173°C
PSA：91.40000
Density:1.224g/cm³
LogP:2.01510
XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:211.07793322
Heavy Atom Count:14
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

4-(4-Methoxybenzyl)-3-thiosemicarbazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 23/24/25
Safety Statements: 22-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CNC(=S)NN

Technology Process of 4-(4-Methoxybenzyl)-3-thiosemicarbazide

There total 4 articles about 4-(4-Methoxybenzyl)-3-thiosemicarbazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 75-15-0,12122-00-8
carbon disulfide

: 2393-23-9
4-methoxy-benzylamine

: 16735-76-5
N-(4-methoxybenzyl)hydrazinecarbothioamide

Guidance literature:: carbon disulfide; 4-methoxy-benzylamine; With triethylamine; In methanol; at 20 ℃;

With methyl iodide; In methanol; at -10 - 20 ℃; for 2h;

With hydrazine hydrate; In methanol; for 4h; Reflux;
DOI:10.1080/07391102.2021.1942212

Reference yield:

: 2393-23-9
4-methoxy-benzylamine

: 16735-76-5
N-(4-methoxybenzyl)hydrazinecarbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / methanol / 2.25 h / 20 - 30 °C

1.2: 2.33 h / -10 - 20 °C

2.1: hydrazine hydrate / ethanol / 2 h / Reflux

With hydrazine hydrate; triethylamine; In methanol; ethanol;
DOI:10.1016/j.bmc.2016.12.012