105219-33-8Relevant articles and documents
Synthesis, crystal structure, molecular docking studies and bio-evaluation of some N4-benzyl-substituted isatin-3-thiosemicarbazones as urease and glycation inhibitors
Pervez, Humayun,Khan, Nazia,Iqbal, Jamshed,Zaib, Sumera,Yaqub, Muhammad,Tahir, Muhammad Nawaz,Naseer, Muhammad Moazzam
, p. 51 - 58 (2018/02/06)
Fifteen N4-benzyl-substituted isatin-3-thiosemicarbazones 5a-o were synthesized and evaluated for their urease and glycation inhibitory potential. Lemna aequinocitalis growth and Artemia salina assays were also done to determine their phytotoxi
HINDERED DISULFIDE DRUG CONJUGATES
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Page/Page column 127; 140, (2017/05/02)
The invention relates generally to disulfide drug conjugates wherein a linker comprising a sulfur-bearing carbon atom substituted with at least one hydrocarbyl or substituted hydrocarbyl is conjugated by a disulfide bond to a cysteine sulfur atom of a targeting carrier, and wherein the linker is further conjugated to a drug moiety. The invention further relates to activated linker-drug conjugates suitable for conjugation to a targeting carrier by a disulfide bond. The invention further relates to methods for preparing hindered disulfide drug conjugates.
SURFUR-CONTAINING ALKALOIDS WITH ANTI-INFLAMMATORY ACTIVITY AND METHOD OF SYNTHESIS
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Paragraph 0059; 0060; 0074; 0077, (2017/05/16)
The extract from Bretschneidera sinensis, surfur-containing alkaloids disclosed in the present aspects have characterized by presented pharmaceutics, cosmetics and foods having functions to improve anti-inflammatory activity.