4-METHYL-2-NITROPHENYL ISOCYANATE

Base Information

• Chemical Name: 4-METHYL-2-NITROPHENYL ISOCYANATE
• CAS No.: 57910-98-2
• Molecular Formula: C8H6N2O3
• Molecular Weight: 178.147
• Hs Code.: 29291090
• Mol file: 57910-98-2.mol

Synonyms:4-METHYL-2-NITROPHENYL ISOCYANATE;Benzene, 1-isocyanato-4-methyl-2-nitro- (9CI);1-isocyanato-4-methyl-2-nitrobenzene

Chemical Property of 4-METHYL-2-NITROPHENYL ISOCYANATE

Chemical Property:

• Vapor Pressure: 0.000957mmHg at 25°C
• Melting Point: 57-61 °C(lit.)
• Refractive Index: 1.578
• Boiling Point: 303°Cat760mmHg
• Flash Point: 137°C
• PSA: 75.25000
• Density: 1.27g/cm³
• LogP: 2.39370
• Sensitive.: Moisture Sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Methyl-2-nitrophenyl isocyanate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 4-Methyl-2-nitrophenyl isocyanate may be used in the preparation 4-methylphenyl analog of 2-[(2-nitrophenyl)amino]furanone.

Technology Process of 4-METHYL-2-NITROPHENYL ISOCYANATE

There total 3 articles about 4-METHYL-2-NITROPHENYL ISOCYANATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 4-methyl-2-nitroaniline (89-62-3) → 2-isocyanato-4-methyl-1-nitrobenzene (57910-98-2)

Guidance literature:

In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.3184/174751913X13663925002708

Reference yield:

4-methyl-2-nitro-aniline; hydrochloride + trichloromethyl chloroformate (503-38-8) → 2-isocyanato-4-methyl-1-nitrobenzene (57910-98-2)

Guidance literature:

In toluene; Heating;

DOI:10.1016/S0968-0896(99)00095-4

Reference yield:

phosgene (75-44-5) + 4-methyl-2-nitroaniline (89-62-3) → 2-isocyanato-4-methyl-1-nitrobenzene (57910-98-2)

Guidance literature:

upstream raw materials:

phosgene

4-methyl-2-nitroaniline

trichloromethyl chloroformate

bis(trichloromethyl) carbonate

Downstream raw materials:

1,3-bis(4-methyl-2-nitrophenyl)urea

N-(4-methyl-2-nitrophenyl)formamide

C₄₉H₅₁N₃O₂₅

(2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-(4-hydroxymethyl-2-nitro-phenylcarbamoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester