Myristoyl glutamic acid

Base Information

• Chemical Name: Myristoyl glutamic acid
• CAS No.: 53576-52-6
• Molecular Formula: C19H35NO5
• Molecular Weight: 357.48
• Hs Code.: 2924199090
• UNII: 31N1S89X64
• DSSTox Substance ID: DTXSID40201791
• Nikkaji Number: J291.061F
• Wikidata: Q27256068
• Mol file: 53576-52-6.mol

Synonyms:Myristoyl glutamic acid;53576-52-6;N-Myristoylglutamic acid;N-Myristoyl-L-glutamic acid;Tetradecanoyl-L-glutamic acid;N-Tetradecanoyl-L-glutamic acid;Glutamic acid, N-myristoyl-, l-;L-Glutamic acid, N-(1-oxotetradecyl)-;(2S)-2-(tetradecanoylamino)pentanedioic acid;31N1S89X64;UNII-31N1S89X64;starbld0015003;SCHEMBL336372;DTXSID40201791;MTJZWYHTZFVEGI-INIZCTEOSA-N;AKOS040753177;MYRISTOYL GLUTAMIC ACID [INCI];Q27256068

Chemical Property of Myristoyl glutamic acid

Chemical Property:

• PSA: 107.19000
• LogP: 4.96200
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 17
• Exact Mass: 357.25152322
• Heavy Atom Count: 25
• Complexity: 384

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCC(=O)NC(CCC(=O)O)C(=O)O
• Isomeric SMILES: CCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O

Technology Process of Myristoyl glutamic acid

There total 6 articles about Myristoyl glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-myristoyl-Glu(OtBu)-OH (1365246-87-2) → N-tetradecanoyl-L-glutamic acid (53576-52-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2012.07.101

Reference yield:

L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + tetradecanoyl chloride (112-64-1) → N-tetradecanoyl-L-glutamic acid (53576-52-6)

Guidance literature:

With water; magnesium oxide; at 0 ℃;

Reference yield:

C23H43NO5 (313946-36-0) → N-tetradecanoyl-L-glutamic acid (53576-52-6)

Guidance literature:

With sodium hydroxide; In methanol;

DOI:10.1002/chem.201002595

upstream raw materials:

L-glutamic acid

tetradecanoyl chloride

C₂₃H₄₃NO₅

L-glutamic acid diethyl ester