Z-Sar-OSu

Base Information

• Chemical Name: Z-Sar-OSu
• CAS No.: 53733-96-3
• Molecular Formula: C15H16N2O6
• Molecular Weight: 320.302
• Hs Code.: 2925190090
• DSSTox Substance ID: DTXSID80512570
• Wikidata: Q82371885
• Mol file: 53733-96-3.mol

Synonyms:Z-Sar-OSu;53733-96-3;Z-N-Me-Gly-OSu;(2,5-dioxopyrrolidin-1-yl) 2-[methyl(phenylmethoxycarbonyl)amino]acetate;2,5-Dioxopyrrolidin-1-yl N-((benzyloxy)carbonyl)-N-methylglycinate;2,5-Dioxopyrrolidin-1-yl N-[(benzyloxy)carbonyl]-N-methylglycinate;SCHEMBL7285217;DTXSID80512570;MFCD00153340;AKOS016003032;CS-0453388;FT-0698547;2,5-dioxo-1-pyrrolidinyl n-((benzyloxy)carbonyl)-n-methylglycinate;2,5-dioxopyrrolidin-1-yl 2-((benzyloxycarbonyl)(methyl)amino)acetate;N-alpha-Benzyloxycarbonyl-sarcosine succinimidyl ester, N-alpha-Benzyloxycarbonyl-N-alpha-Methyl-glycine succinimidyl ester

Chemical Property of Z-Sar-OSu

Chemical Property:

• PSA: 93.22000
• LogP: 0.80010
• Storage Temp.: -15°C
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 320.10083623
• Heavy Atom Count: 23
• Complexity: 470

Purity/Quality:

98% ^*data from raw suppliers

Z-N-methylglycine N-hydroxysuccinimide ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(CC(=O)ON1C(=O)CCC1=O)C(=O)OCC2=CC=CC=C2

Technology Process of Z-Sar-OSu

There total 1 articles about Z-Sar-OSu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + N-(Benzyloxycarbonyl)sarcosine (39608-31-6) → N-(benzyloxycarbonyl)sarcosine N-hydroxysuccinimide ester (53733-96-3)

Guidance literature:

With dicyclohexyl-carbodiimide; In 1,2-dimethoxyethane; at 0 ℃;

DOI:10.1021/jm00151a005

Reference yield: 90.0%

ethyl>phosphonic acid (71930-98-8) + N-(benzyloxycarbonyl)sarcosine N-hydroxysuccinimide ester (53733-96-3) → ethyl>phosphonic acid (71930-99-9)

Guidance literature:

With triethylamine; In water; N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1021/jm00151a005

Reference yield: 76.0%

propylamine (107-10-8,42939-71-9) + N-(benzyloxycarbonyl)sarcosine N-hydroxysuccinimide ester (53733-96-3) → ZSarNHPr (1616849-82-1)

Guidance literature:

In 1,2-dimethoxyethane; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1002/ejoc.201400154

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

N-(Benzyloxycarbonyl)sarcosine

Downstream raw materials:

ethyl>phosphonic acid

monobenzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-sarcosyl-glycyl-L-norvalyl)amino]-ethylphosphonic acid

monobenzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-sarcosyl-L-alanyl)amino]-ethylphosphonic acid

monobenzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-sarcosyl-glycyl-L-alanyl)amino]-ethylphosphonic acid