Methyl 2,3-dihydro-4-furoate

Base Information

• Chemical Name: Methyl 2,3-dihydro-4-furoate
• CAS No.: 53750-81-5
• Molecular Formula: C6H8O3
• Molecular Weight: 128.12592
• Hs Code.: 2932190090
• Mol file: 53750-81-5.mol

Synonyms:Methyl 2,3-dihydro-4-furoate;3-Furancarboxylic acid, 4,5-dihydro-, methyl ester (9CI)

Chemical Property of Methyl 2,3-dihydro-4-furoate

Chemical Property:

• PSA: 35.53000
• LogP: 0.46360

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2,3-dihydro-4-furoate

There total 3 articles about Methyl 2,3-dihydro-4-furoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(2S,3S)-2-Tributylstannanyl-tetrahydro-furan-3-carboxylic acid methyl ester → 4,5-dihydro-furan-3-carboxylic acid methyl ester (53750-81-5)

Guidance literature:

With ammonium cerium(IV) nitrate; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tetlet.2006.02.161

Reference yield:

methanol (67-56-1) + 3-trichloroacetyl-4,5-dihydrofuran (83124-80-5) → 4,5-dihydro-furan-3-carboxylic acid methyl ester (53750-81-5) + 2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester (89941-77-5,143789-16-6,143789-17-7,117632-34-5,117632-35-6)

Guidance literature:

With potassium carbonate;

DOI:10.1016/S0040-4039(98)00075-6

Reference yield:

2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester (89941-77-5,143789-16-6,143789-17-7,117632-34-5,117632-35-6) → 4,5-dihydro-furan-3-carboxylic acid methyl ester (53750-81-5)

Guidance literature:

With sulfuric acid; at 125 ℃;

upstream raw materials:

2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester

methanol

3-trichloroacetyl-4,5-dihydrofuran

Downstream raw materials:

4,5-dihydrofuran-3-carboxylic acid

methyl tetrahydrofuran-3-carboxylate