Methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate

Base Information

• Chemical Name: Methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate
• CAS No.: 58298-68-3
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.18854
• Hs Code.: 2933998090
• European Community (EC) Number: 962-767-6
• DSSTox Substance ID: DTXSID60483355
• Wikidata: Q82320616
• Mol file: 58298-68-3.mol

Synonyms:METHYL 5-FORMYL-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE;58298-68-3;SCHEMBL15331397;DTXSID60483355;AKOS006329848;SB62389;EN300-6487460;Z1198184407

Chemical Property of Methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate

Chemical Property:

• PSA: 59.16000
• LogP: 1.23060
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 181.07389321
• Heavy Atom Count: 13
• Complexity: 217

Purity/Quality:

97% ^*data from raw suppliers

Methyl5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(NC(=C1C(=O)OC)C)C=O

Technology Process of Methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate

There total 4 articles about Methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methanol (67-56-1) + 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (253870-02-9) → methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate (58298-68-3)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 48h; Reflux; Inert atmosphere;

DOI:10.1055/s-0030-1258769

Reference yield: 90.0%

5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (253870-02-9) + dimethyl sulfate (77-78-1) → methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate (58298-68-3)

Guidance literature:

With potassium carbonate; In acetone; at 23 ℃; for 12h;

DOI:10.1021/ol5036936

Reference yield:

5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (253870-02-9) + methyl chloroformate (79-22-1) → methyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate (58298-68-3)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1016/j.ejmech.2014.07.108

upstream raw materials:

methanol

5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

methyl chloroformate

dimethyl sulfate

Downstream raw materials:

ethyl (5-formyl-2,4-dimethyl-1H-pyrrole)-3-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 58298-68-3 METHYL 5-FORMYL-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send