5-(3,4-Dichlorophenyl)furan-2-carboxylic acid

Base Information

Chemical Name:5-(3,4-Dichlorophenyl)furan-2-carboxylic acid
CAS No.:54023-01-7
Molecular Formula:C11H6Cl2O3
Molecular Weight:257.073
Hs Code.:2932190090
DSSTox Substance ID:DTXSID50352980
Wikidata:Q82130426
ChEMBL ID:CHEMBL4125811
Mol file:54023-01-7.mol

Synonyms:5-(3,4-dichlorophenyl)furan-2-carboxylic acid;54023-01-7;5-(3,4-Dichlorophenyl)-2-furoic acid;2-Furancarboxylic acid, 5-(3,4-dichlorophenyl)-;5-(3 4-DICHLOROPHENYL)-2-FURONIC ACID;CHEMBL4125811;DTXSID50352980;BBL019904;MFCD02257992;STK027509;AKOS000452762;SB61660;VS-07026;BB 0245457;CS-0315850;5-(34-DICHLOROPHENYL)-2-FURONICACID;5-(3,4-Dichlorophenyl)-2-furoic acid, 97%;AS-871/13774292;5-(3,4-Dichloro-phenyl)-furan-2-carboxylic acid;E0H

Suppliers and Price of 5-(3,4-Dichlorophenyl)furan-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(3,4-Dichlorophenyl)-2-furoic acid
1g
$ 160.00

Sigma-Aldrich
5-(3,4-Dichlorophenyl)-2-furoic acid 97%
5g
$ 177.00

Sigma-Aldrich
5-(3,4-Dichlorophenyl)-2-furoic acid 97%
1g
$ 50.60

Crysdot
5-(3,4-Dichlorophenyl)furan-2-carboxylicacid 95+%
10g
$ 367.00

American Custom Chemicals Corporation
5-(3,4-DICHLOROPHENYL)-2-FUROIC ACID 95.00%
25G
$ 3565.49

American Custom Chemicals Corporation
5-(3,4-DICHLOROPHENYL)-2-FUROIC ACID 95.00%
10G
$ 2255.72

American Custom Chemicals Corporation
5-(3,4-DICHLOROPHENYL)-2-FUROIC ACID 95.00%
5G
$ 1661.47

Alichem
5-(3,4-Dichlorophenyl)furan-2-carboxylicacid
10g
$ 367.00

AK Scientific
5-(3,4-Dichlorophenyl)-2-furoic acid
100mg
$ 128.00

Total 10 raw suppliers

Chemical Property of 5-(3,4-Dichlorophenyl)furan-2-carboxylic acid

Chemical Property:

Vapor Pressure:5.57E-08mmHg at 25°C
Melting Point:236-240 °C(lit.)
Refractive Index:1.604
Boiling Point:425°C at 760 mmHg
PKA:2.83±0.10(Predicted)
Flash Point:210.8°C
PSA：50.44000
Density:1.477g/cm³
LogP:3.95160
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:255.9693994
Heavy Atom Count:16
Complexity:272

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-(3,4-Dichlorophenyl)-2-furoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=C(C=C1C2=CC=C(O2)C(=O)O)Cl)Cl
Uses 5-(3,4-Dichlorophenyl)-2-furoic acid is a reactant in the preparation of dantrolene (D185000) which has a potential to treat vascular dysfunction.

Technology Process of 5-(3,4-Dichlorophenyl)furan-2-carboxylic acid

There total 7 articles about 5-(3,4-Dichlorophenyl)furan-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 52130-34-4
5-(3,4-dichlorophenyl)furfural

: 54023-01-7
5-(3,4-dichlorophenyl)furan-2-carboxylic acid

Guidance literature:: With silver nitrate; sodium hydroxide; In ethanol; water; at 60 ℃; for 2h; Heating;
DOI:10.1021/acs.jmedchem.1c01810

Reference yield: 50.0%

: 88-14-2
2-furanoic acid

: 95-76-1
m,p-dichloroaniline

: 54023-01-7
5-(3,4-dichlorophenyl)furan-2-carboxylic acid

Guidance literature:: m,p-dichloroaniline; With hydrogenchloride; sodium nitrite;

2-furanoic acid; With copper(II) chloride dihydrate; In water; acetone; at 0 - 30 ℃;
DOI:10.1134/S1070428009040125