(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid
CAS No.:62522-93-4
Molecular Formula:C12H12FNO3
Molecular Weight:237.231
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30494630
Wikidata:Q82342134

Synonyms:(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid;62522-93-4;(4-fluorobenzoyl)-L-proline;(2S)-1-(4-FLUOROBENZOYL)PYRROLIDINE-2-CARBOXYLIC ACID;N-(4-Fluorobenzoyl)-L-proline;1-(4-Fluorobenzoyl)-L-proline;MFCD09757450;SCHEMBL6290808;DTXSID30494630;AKOS016843879;DS-4564;s10042;CS-0155467;A868450

Suppliers and Price of (S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
(4-fluorobenzoyl)-L-proline 98%
5g
$ 224.00

Chemenu
(4-fluorobenzoyl)-L-proline 98%
10g
$ 393.00

American Custom Chemicals Corporation
1-(4-FLUOROBENZOYL)-L-PROLINE 95.00%
1G
$ 590.00

American Custom Chemicals Corporation
1-(4-FLUOROBENZOYL)-L-PROLINE 95.00%
5MG
$ 500.08

Alichem
(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylicacid
10g
$ 386.71

Alichem
(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylicacid
5g
$ 220.95

AK Scientific
(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylicacid
5g
$ 311.00

AK Scientific
(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylicacid
1g
$ 157.00

Activate Scientific
(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid 98+% ee
5 g
$ 353.00

Activate Scientific
(S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid 98+% ee
1 g
$ 151.00

Total 14 raw suppliers

Chemical Property of (S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.41E-08mmHg at 25°C
Refractive Index:1.581
Boiling Point:441.6°C at 760 mmHg
PKA:5.29±0.10(Predicted)
Flash Point:220.9°C
PSA：57.61000
Density:1.369g/cm³
LogP:1.45280
Storage Temp.:2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:237.08012141
Heavy Atom Count:17
Complexity:313

Purity/Quality:

97% ^*data from raw suppliers

(4-fluorobenzoyl)-L-proline 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(N(C1)C(=O)C2=CC=C(C=C2)F)C(=O)O
Isomeric SMILES:C1C[C@H](N(C1)C(=O)C2=CC=C(C=C2)F)C(=O)O

Technology Process of (S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid

There total 1 articles about (S)-1-(4-Fluorobenzoyl)pyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 403-43-0
4-fluorobenzoyl chloride

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 62522-93-4
1-(4-fluorbenzoyl)-pyrrolidine-2-carboxylic acid

Guidance literature:: 4-fluorobenzoyl chloride; L-proline; With sodium hydroxide; In water; at 20 ℃; for 1h;

With hydrogenchloride; In water; Cooling with ice;

Reference yield: 89.0%

: 62522-93-4
1-(4-fluorbenzoyl)-pyrrolidine-2-carboxylic acid

: 4891-38-7
phenylpropynoic acid methyl ester

: 3-(4-fluorphenyl)-2-phenyl-6,7-dihydro-5H-pyrrolizine-1-carboxylic acid methyl ester

Guidance literature:: phenylpropynoic acid methyl ester; With acetic anhydride; at 140 ℃;

1-(4-fluorbenzoyl)-pyrrolidine-2-carboxylic acid; at 128 ℃; for 20h;