N-ethylacrylamide

Base Information

• Chemical Name: N-ethylacrylamide
• CAS No.: 5883-17-0
• Molecular Formula: C5H9NO
• Molecular Weight: 99.1326
• European Community (EC) Number: 696-277-6
• DSSTox Substance ID: DTXSID10430697
• Nikkaji Number: J100.719J
• Wikidata: Q82244377
• Mol file: 5883-17-0.mol

Synonyms:N-ethylacrylamide;5883-17-0;N-ETHYL ACRYLAMIDE;N-ethylprop-2-enamide;2-Propenamide, N-ethyl-;Acrylamide, N-ethyl-;DTXSID10430697;SWPMNMYLORDLJE-UHFFFAOYSA-N;AMY36703;AB9195;MFCD00048514;MFCD03458133;AKOS009808478;CS-W013719;25215-59-2;AS-56872;A8303;BB 0261739;FT-0695176;EN300-6477121;N-Ethylacrylamide, contains MEHQ as inhibitor, 99% (HPLC)

Chemical Property of N-ethylacrylamide

Chemical Property:

• Vapor Pressure: 0.117mmHg at 25°C
• Refractive Index: 1.423
• Boiling Point: 219.759 °C at 760 mmHg
• PKA: 15.13±0.46(Predicted)
• Flash Point: 114.077 °C
• PSA: 29.10000
• Density: 0.884 g/cm³
• LogP: 0.69940
• Storage Temp.: 2-8°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 99.068413911
• Heavy Atom Count: 7
• Complexity: 78.1

Purity/Quality:

99% ^*data from raw suppliers

N-Ethylacrylamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-52-22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNC(=O)C=C
• Uses: Application Statement: monomer for drug delivery; thermal responsive polymers; solutions with specific LCSTs

Technology Process of N-ethylacrylamide

There total 8 articles about N-ethylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.43%

ethylamine (75-04-7,85404-22-4) + acryloyl chloride (814-68-6,25189-84-8) → N-ethyl-2-propenamide (5883-17-0,25215-59-2)

Guidance literature:

With triethylamine; In acetonitrile; at 0 - 20 ℃; for 16h;

Reference yield:

Acrylsaeure-N-allyl-N-aethylamid (57934-23-3) → N-ethyl-2-propenamide (5883-17-0,25215-59-2)

Guidance literature:

With palladium dichloride; Heating;

Reference yield:

ethylamine (75-04-7,85404-22-4) + acetylene (74-86-2,25067-58-7) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → N-ethyl-2-propenamide (5883-17-0,25215-59-2)

Guidance literature:

at 160 ℃; unter Druck;

upstream raw materials:

ethylamine

acryloyl chloride

Acrylsaeure-N-allyl-N-aethylamid

hydrogenchloride

Downstream raw materials:

1-phenylpyrazolidin-3-one

(Z)-N-Ethyl-3-(1-methyl-2-oxo-cyclohexylsulfanyl)-acrylamide