(E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate

Base Information

Chemical Name:(E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate
CAS No.:521302-69-2
Molecular Formula:C₁₅H₂₆N₂O₄
Molecular Weight:298.382
Hs Code.:
Mol file:521302-69-2.mol

Synonyms:(E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate

Suppliers and Price of (E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
(E)-TERT-BUTYL4-(1-AMINO-3-ETHOXY-3-OXOPROP-1-ENYL)PIPERIDINE-1-CARBOXYLATE 95
1g
$ 1217.00

American Custom Chemicals Corporation
(E)-TERT-BUTYL 4-(1-AMINO-3-ETHOXY-3-OXOPROP-1-ENYL)PIPERIDINE-1-CARBOXYLATE 95.00%
5MG
$ 500.75

Total 6 raw suppliers

Chemical Property of (E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate

Chemical Property:

PSA：81.86000
LogP:2.67740

Purity/Quality:

98%Min ^*data from raw suppliers

(E)-TERT-BUTYL4-(1-AMINO-3-ETHOXY-3-OXOPROP-1-ENYL)PIPERIDINE-1-CARBOXYLATE 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate

There total 2 articles about (E)-tert-butyl 4-(1-amino-3-ethoxy-3-oxoprop-1-enyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 479630-08-5
4-(2-ethoxycarbonylacetyl)piperidine-1-carboxylic acid tert-butyl ester

: 521302-69-2
4-(1-amino-2-ethoxycarbonyl-vinyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With ammonium acetate; In ethanol; Heating;
DOI:10.1016/S0040-4039(03)00034-0

Reference yield:

: 84358-13-4,174286-31-8
N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

: 521302-69-2
4-(1-amino-2-ethoxycarbonyl-vinyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: DMAP; DCC / CH₂Cl₂

1.2: 97 percent / Heating

2.1: 98 percent / ammonium acetate / ethanol / Heating

With ammonium acetate; dmap; dicyclohexyl-carbodiimide; In ethanol; dichloromethane;
DOI:10.1016/S0040-4039(03)00034-0

Reference yield:

: 521302-69-2
4-(1-amino-2-ethoxycarbonyl-vinyl)-piperidine-1-carboxylic acid tert-butyl ester

: 3-(4-imidazol-1-yl-phenylcarbamoyl)-6-methyl-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / ethanol / Heating

2: 99 percent / aq. NaOH / methanol

3: HBTU; Et₃N / acetonitrile

With sodium hydroxide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In methanol; ethanol; acetonitrile; 1: Bohlmann-Rahtz reaction;
DOI:10.1016/S0040-4039(03)00034-0