2,4-Dimethylthiophene-3-carboxylic Acid

Base Information

Chemical Name:2,4-Dimethylthiophene-3-carboxylic Acid
CAS No.:503308-96-1
Molecular Formula:C7H8O2S
Molecular Weight:156.2
Hs Code.:2934999090
European Community (EC) Number:886-465-8
Mol file:503308-96-1.mol

Synonyms:2,4-Dimethylthiophene-3-carboxylic Acid;503308-96-1;SCHEMBL4236884;NRYCOTXIOMJBLD-UHFFFAOYSA-N;MFCD18819341;2,4-Dimethylthiophene-3-carboxylicAcid;CS-0195974;EN300-701498

Suppliers and Price of 2,4-Dimethylthiophene-3-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
2,4-Dimethylthiophene-3-carboxylicacid 97%
1g
$ 545.00

AOBChem
2,4-Dimethylthiophene-3-carboxylicacid 97%
1g
$ 421.00

AOBChem
2,4-Dimethylthiophene-3-carboxylic acid 97%
500mg
$ 301.00

AOBChem
2,4-Dimethylthiophene-3-carboxylicacid 97%
5g
$ 1505.00

Alichem
2,4-Dimethylthiophene-3-carboxylicacid
1g
$ 606.96

Alichem
2,4-Dimethylthiophene-3-carboxylicacid
250mg
$ 243.00

Total 2 raw suppliers

Chemical Property of 2,4-Dimethylthiophene-3-carboxylic Acid

Chemical Property:

Melting Point:165-166 °C
Boiling Point:278.2±35.0 °C(Predicted)
PKA:4.52±0.40(Predicted)
PSA：65.54000
Density:1.259±0.06 g/cm3(Predicted)
LogP:2.06310
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:156.02450067
Heavy Atom Count:10
Complexity:147

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dimethylthiophene-3-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CSC(=C1C(=O)O)C

Technology Process of 2,4-Dimethylthiophene-3-carboxylic Acid

There total 7 articles about 2,4-Dimethylthiophene-3-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 78071-30-4
4-methylthiophene-3-carboxylic acid

: 74-88-4
methyl iodide

: 503308-96-1
2,4-dimethylthiophene-3-carboxylic acid

Guidance literature:: 4-methylthiophene-3-carboxylic acid; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

Reference yield:

: 30318-99-1
3-bromo-4-methylthiophene

: 503308-96-1
2,4-dimethylthiophene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -78 °C

1.2: 0.5 h / -78 °C

2.1: n-butyllithium / hexane; tetrahydrofuran / 0.17 h / -78 °C

2.2: 15.5 h / -78 - 20 °C

With n-butyllithium; In tetrahydrofuran; hexane;

Reference yield:

: 79485-96-4
3-bromo-2,4-dimethylthiophene

: 503308-96-1
2,4-dimethylthiophene-3-carboxylic acid

Guidance literature:: With ethyl bromide; diethyl ether; magnesium; Behandeln des Reaktionsgemisches mit Kohlendioxid;
DOI:10.1021/jo01366a013