5-(pyrrolidin-1-yl)-3,4-dihydro-2H-pyrrole

Base Information

• Chemical Name: 5-(pyrrolidin-1-yl)-3,4-dihydro-2H-pyrrole
• CAS No.: 1004-83-7
• Molecular Formula: C8H14 N2
• Molecular Weight: 138.213
• Mol file: 1004-83-7.mol

Synonyms:Pyrrolidine,1-(1-pyrrolin-2-yl)- (7CI,8CI); NSC 317042

Chemical Property of 5-(pyrrolidin-1-yl)-3,4-dihydro-2H-pyrrole

Chemical Property:

• Vapor Pressure: 0.0154mmHg at 25°C
• Boiling Point: 256.5°C at 760 mmHg
• Flash Point: 108.9°C
• Density: 1.15g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(pyrrolidin-1-yl)-3,4-dihydro-2H-pyrrole

There total 2 articles about 5-(pyrrolidin-1-yl)-3,4-dihydro-2H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

pyrrolidine (123-75-1) + iodobenzene (591-50-4) → 2-phenyl-1-pyrroline (700-91-4) + 2-pyrrolidino-Δ1-pyrroline (1004-83-7)

Guidance literature:

With tert-butylethylene; RhCl(CO)(PFur₃)2; caesium carbonate; In 1,4-dioxane; at 120 ℃; for 10h;

DOI:10.1021/ja045402b

Reference yield: 5.0%

pyrrolidine (123-75-1) + iodobenzene (591-50-4) → 2-phenyl-1-pyrroline (700-91-4) + N-phenylpyrrolidine (4096-21-3) + 2-pyrrolidino-Δ1-pyrroline (1004-83-7) + 5-([1,1'-biphenyl]-2-yl)-3,4-dihydro-2H-pyrrole

Guidance literature:

pyrrolidine; iodobenzene; With tert-butylethylene; RhCl(CO)(PFur₃)2; caesium carbonate; In 1,4-dioxane; at 120 ℃; for 10h;

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 0.5h;

DOI:10.1021/ja045402b

Reference yield: 95.0%

2-pyrrolidino-Δ1-pyrroline (1004-83-7) → 2-pyrrolidinon (616-45-5)

Guidance literature:

With 5.4 wt% Au/CeO2; water; oxygen; In diethylene glycol dimethyl ether; at 160 ℃; for 6.5h; under 760.051 Torr; Catalytic behavior; Schlenk technique;

DOI:10.1007/s10562-016-1834-2

upstream raw materials:

pyrrolidine

iodobenzene

Downstream raw materials:

2-pyrrolidinon

Refernces