Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate

Base Information

• Chemical Name: Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate
• CAS No.: 597562-79-3
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• European Community (EC) Number: 827-662-0
• Mol file: 597562-79-3.mol

Synonyms:methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate;597562-79-3;1,2,3,4-TETRAHYDRO-QUINOLINE-7-CARBOXYLIC ACID METHYL ESTER;SCHEMBL554225;BDMQUHKEECRIDC-UHFFFAOYSA-N;SB37861;BS-29126;CS-0107313;D76727;EN300-374211;methyl1,2,3,4-tetrahydroquinoline-7-carboxylate;A914196;Methyl 1,2,3,4-tetrahydro-quinoline-7-carboxylate;1,2,3,4-Tetrahydroquinoline-7-carboxylic acid methyl ester

Chemical Property of Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate

Chemical Property:

• PSA: 38.33000
• LogP: 2.77130
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 191.094628657
• Heavy Atom Count: 14
• Complexity: 217

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-Tetrahydro-quinoline-7-carboxylicacidmethylester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC2=C(CCCN2)C=C1

Technology Process of Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate

There total 2 articles about Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

ethanol (64-17-5) + methyl 3-amino-4-(hydroxymethyl)benzoate → methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate (597562-79-3)

Guidance literature:

With nanosized Ni particles supported on Ni- and Al-containing layered double oxides; at 120 ℃; for 26h; Inert atmosphere; Sealed tube;

DOI:10.1021/acscatal.9b03245

Reference yield: 80.0%

quinoline-7-carboxylic acid methyl ester (51552-68-2) → methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate (597562-79-3)

Guidance literature:

With perchloric acid; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; In water; isopropyl alcohol; at 85 ℃; for 17h;

Reference yield: 93.0%

methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate (597562-79-3) + 2-methoxy-5-methylbenzene sulfonyl chloride (88040-86-2) → 1-(2-methoxy-5-methyl-benzenesulfonyl)-1,2,3,4-tetrahydro-quinoline-7-carboxylic acid methyl ester (1034776-74-3)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 18h;

upstream raw materials:

quinoline-7-carboxylic acid methyl ester

ethanol

Downstream raw materials:

1-(2-methoxy-5-methyl-benzenesulfonyl)-1,2,3,4-tetrahydro-quinoline-7-carboxylic acid methyl ester

methyl 1-phenyl-1,2,3,4-tetrahydroquinoline-7-carboxylate

(1-phenyl-1,2,3,4-tetrahydroquinolin-7-yl)methanol

(4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-1,2,3,4-tetrahydro-quinoline-7-carbonyl]-amino}-phenyl)-acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 597562-79-3 1,2,3,4-TETRAHYDRO-QUINOLINE-7-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send