d-Noradrenaline bitartrate

Base Information

Chemical Name:d-Noradrenaline bitartrate
CAS No.:636-88-4
Deprecated CAS:893-73-2,18332-51-9,30337-97-4
Molecular Formula:C16H23NO15
Molecular Weight:319.268
Hs Code.:
European Community (EC) Number:211-268-5
DSSTox Substance ID:DTXSID80212982
Mol file:636-88-4.mol

Synonyms:636-88-4;(S)-(+)-Norepinephrine L-bitartrate;d-Noradrenaline bitartrate;(+)-Noradrenaline bitartrate;D-Norepinephrine d-bitartrate;S-(+)-Norepinephrine bitartrate;D-Norepinephrine bitartrate;(+)-Norepinephrine bitartrate;4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol;(2R,3R)-2,3-dihydroxybutanedioic acid;(+)-(S)-Norepinephrine bitartrate;(+)-Norepinephrine (+)-bitartrate;EINECS 211-268-5;C8H11NO3.C4H6O6;(S)-4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol (2R,3R)-2,3-dihydroxysuccinate;(S)-beta,3,4-Trihydroxyphenethylammonium (R-(R*,R*))-hydrogen tartrate;(S)-beta,3,4-trihydroxyphenethylammonium [R-(R*,R*)]-hydrogen tartrate;D-Norepinephrine hydrogen tartrate salt;( )-Noradrenaline bitartrate;( )-Norepinephrine bitartrate;D-(+)-Noradrenaline Tartrate;S-( )-Norepinephrine bitartrate;DTXSID80212982;( )-(S)-Norepinephrine bitartrate;( )-Norepinephrine ( )-bitartrate;AKOS016006128;CS-W009900;C8-H11-N-O3.C4-H6-O6;(S)-(+)-Norepinephrine L-bitartrate, 99%;E84787;A868063;4-[(1S)-2-AMINO-1-HYDROXYETHYL]-2-HYDROXY-PHENOL D-(-)-TARTRATE;Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (+)-, tartrate (1:1);Benzyl alcohol, .alpha.-(aminomethyl)-3,4-dihydroxy-, ()-, tartrate (1:1) (salt);1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (S)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt);1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (S)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)

Suppliers and Price of d-Noradrenaline bitartrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+)-NoradrenalineBitartrate
10mg
$ 180.00

Sigma-Aldrich
(S)-(+)-Norepinephrine L-bitartrate 99%
1g
$ 990.00

Medical Isotopes, Inc.
(+)-NoradrenalineBitartrate
1 g
$ 650.00

Medical Isotopes, Inc.
(+)-NoradrenalineBitartrate
10 g
$ 2200.00

Matrix Scientific
(S)-(+)-Norepinephrine L-bitartrate 95+%
250mg
$ 189.00

Matrix Scientific
(S)-(+)-Norepinephrine L-bitartrate 95+%
5g
$ 1183.00

Matrix Scientific
(S)-(+)-Norepinephrine L-bitartrate 95+%
1g
$ 420.00

Biosynth Carbosynth
4-[(1S)-2-Amino-1-Hydroxy-Ethyl]Benzene-1,2-Diol
100 mg
$ 105.00

Biosynth Carbosynth
4-[(1S)-2-Amino-1-Hydroxy-Ethyl]Benzene-1,2-Diol
50 mg
$ 70.00

Biosynth Carbosynth
4-[(1S)-2-Amino-1-Hydroxy-Ethyl]Benzene-1,2-Diol
500 mg
$ 325.00

Total 19 raw suppliers

Chemical Property of d-Noradrenaline bitartrate

Chemical Property:

Vapor Pressure:1.3E-08mmHg at 25°C
Melting Point:166 °C (dec.)(lit.)
Boiling Point:442.6°C at 760 mmHg
Flash Point:221.5°C
PSA：201.77000
LogP:-1.33240
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:5
Exact Mass:319.09033112
Heavy Atom Count:22
Complexity:276

Purity/Quality:

97% ^*data from raw suppliers

(+)-NoradrenalineBitartrate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T,Xn
Statements: 25-36/37/38-20/21/22
Safety Statements: 36/37-45-37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(CN)O)O)O.C(C(C(=O)O)O)(C(=O)O)O
Isomeric SMILES:C1=CC(=C(C=C1[C@@H](CN)O)O)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

Technology Process of d-Noradrenaline bitartrate

There total 3 articles about d-Noradrenaline bitartrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87-69-4,138508-61-9
L-Tartaric acid

: (x)C₂H₂O₄*C₈H₁₁NO₃

: 636-88-4
(+)-Norepinephrine bitartrate

Guidance literature:: (x)C₂H₂O₄*C₈H₁₁NO₃; With sodium metabisulfite; ethylenediaminetetraacetic acid; potassium carbonate; In water; at 60 ℃;

L-Tartaric acid; In ethanol; water; at 50 ℃;

Reference yield:

: 87-69-4,138508-61-9
L-Tartaric acid

: C₂H₄O₂*C₁₅H₁₅NO₃

: 636-88-4
(+)-Norepinephrine bitartrate

Guidance literature:: C₂H₄O₂*C₁₅H₁₅NO₃; With formic acid; C₃₄H₃₈N₂O₂RuS; In methanol; water; for 2h; Reflux;

With formic acid; palladium 10% on activated carbon; In methanol; water; for 3h; Reflux;

L-Tartaric acid; In methanol; water; Solvent;

Reference yield:

: 99-40-1
2-chloro-3',4'-dihydroxyacetophenone

: 636-88-4
(+)-Norepinephrine bitartrate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / water / 2 h / 30 - 50 °C / Inert atmosphere; Large scale

1.2: 10 - 25 °C / Large scale

2.1: C₃₄H₃₈N₂O₂RuS; formic acid / water; methanol / 2 h / Reflux

2.2: 3 h / Reflux

With formic acid; C₃₄H₃₈N₂O₂RuS; triethylamine; In methanol; water;