1-NAPHTHOYL CYANIDE

Base Information

• Chemical Name: 1-NAPHTHOYL CYANIDE
• CAS No.: 14271-86-4
• Molecular Formula: C12H7 N O
• Molecular Weight: 181.194
• Hs Code.: 2926909090
• Mol file: 14271-86-4.mol

Synonyms:1-Naphthaleneglyoxylonitrile(7CI,8CI); 1-Naphthalenecarbonyl cyanide; 1-Naphthoyl cyanide; a-Naphthoylnitrile; a-Oxo-1-naphthaleneacetonitrile

Chemical Property of 1-NAPHTHOYL CYANIDE

Chemical Property:

• Melting Point: 100 °C
• Boiling Point: 182 °C / 15mmHg
• Flash Point: 150.7oC
• PSA: 40.86000
• Density: 1.22g/cm3
• LogP: 2.54608

Purity/Quality:

97% ^*data from raw suppliers

1-NaphthalenecarbonylCyanide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-NAPHTHOYL CYANIDE

There total 17 articles about 1-NAPHTHOYL CYANIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(1-naphthyl)-5-azido-1,3,4-oxadiazole (84143-78-2) → 1-naphthoyl cyanide (14271-86-4)

Guidance literature:

In dichloromethane; for 0.67h; Irradiation;

DOI:10.1021/ja00342a044

Reference yield: 65.0%

1-naphthyl cyanohydrin (121950-19-4,136983-94-3,143954-79-4,97798-35-1) → 1-naphthoyl cyanide (14271-86-4)

Guidance literature:

With tert.-butylhydroperoxide; tris(triphenylphosphine)ruthenium(II) chloride; In benzene; for 24h; Ambient temperature;

DOI:10.1016/S0040-4039(00)61966-4

Reference yield: 20.0%

N,N,N',N',N'',N''-Hexamethylguanidiniumcyanid (68897-45-0) + naphthalene-1-carbonic acid chloride (879-18-5) → 1-naphthoyl cyanide (14271-86-4) + N,N,N',N',N'',N''-hexamethylguanidinium chloride (30388-20-6)

Guidance literature:

In acetonitrile; at 20 ℃; for 2h;

upstream raw materials:

naphthalen-1-ylacetonitrile

naphthalene

carbonyl cyanide

1-naphthyl cyanohydrin

Downstream raw materials:

hydrogen cyanide

1-naphthalenecarboxylic acid

1-naphthanilide

N-benzyl-1-naphthamide