Phosphoribosylformylglycineamidine

Base Information

• Chemical Name: Phosphoribosylformylglycineamidine
• CAS No.: 6157-85-3
• Molecular Formula: C8H16N3O8P
• Molecular Weight: 313.2
• Mol file: 6157-85-3.mol

Synonyms:Phosphoribosylformylglycineamidine;CHEBI:190761;[(2R,3S,4R,5R)-5-[(E)-(1-amino-2-ormamidoethylidene)amino]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

Chemical Property of Phosphoribosylformylglycineamidine

Chemical Property:

• XLogP3: -4.6
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 6
• Exact Mass: 313.06750147
• Heavy Atom Count: 20
• Complexity: 413

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C1C(C(C(O1)N=C(CNC=O)N)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@H]([C@@H](O1)/N=C(\CNC=O)/N)O)O)OP(=O)(O)O

Technology Process of Phosphoribosylformylglycineamidine

There total 1 articles about Phosphoribosylformylglycineamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-ribose 5-phosphate (34980-66-0) + L-glutamine (56-85-9,26700-71-0) → N-formylglycinamidine ribonucleotide (6157-85-3)

Guidance literature:

With ammonium hydroxide; ATP; magnesium chloride; In aq. phosphate buffer; at 37 ℃; for 4h; pH=7.4; Enzymatic reaction;

DOI:10.1371/journal.pone.0208947

upstream raw materials:

D-ribose 5-phosphate

L-glutamine

Refernces