1-(2-MESITYLENE)-1,3-BUTANEDIONE

Base Information

• Chemical Name: 1-(2-MESITYLENE)-1,3-BUTANEDIONE
• CAS No.: 6450-57-3
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Hs Code.: 2914399090
• Mol file: 6450-57-3.mol

Synonyms:1-Mesityl-1,3-butanedione;2,4,6-Trimethylbenzoylacetone;Mesitoylacetone;1,3-Butanedione,1-mesityl- (7CI,8CI);1-(2,4,6-Trimethylphenyl)-1,3-butanedione;1-(2-Mesitylene)-1,3-butanedione;

Chemical Property of 1-(2-MESITYLENE)-1,3-BUTANEDIONE

Chemical Property:

• Melting Point: 45 °C
• Boiling Point: 319.8 °C at 760 mmHg
• Flash Point: 119.8 °C
• PSA: 34.14000
• Density: 1.021 g/cm³
• LogP: 2.77360
• Solubility.: within almost transparency in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(2-Mesitylene)-1,3-butanedione ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-MESITYLENE)-1,3-BUTANEDIONE

There total 6 articles about 1-(2-MESITYLENE)-1,3-BUTANEDIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,4,6-Trimethylacetophenone (1667-01-2,51885-97-3) → 1-(2,4,6-trimethylphenyl)-1,3-butanedione (6450-57-3)

Guidance literature:

With dibenzo-18-crown-6; ethanol; sodium hydride; In tetrahydrofuran; 1.) r.t, 0.5 h, 2.) reflux, 4 h;

DOI:10.1055/s-1991-26416

Reference yield: 96.0%

2,4,6-Trimethylacetophenone (1667-01-2,51885-97-3) → 1-(2,4,6-trimethylphenyl)-1,3-butanedione (6450-57-3)

Guidance literature:

With dibenzo-18-crown-6; ethanol; CH₃COOR; sodium hydride; In tetrahydrofuran; 1.) r.t., 0.5 h, 2.) reflux, 4 h; other ester;

DOI:10.1055/s-1991-26416

Reference yield: 28.0%

acetic anhydride (108-24-7) + 1,3,5-trimethyl-benzene (108-67-8) → 1-(2,4,6-trimethylphenyl)-1,3-butanedione (6450-57-3)

Guidance literature:

With boron trifluoride diethyl etherate;

upstream raw materials:

2,4,6-Trimethylacetophenone

ethylmagnesium bromide

acetic anhydride

1,3,5-trimethyl-benzene

Downstream raw materials:

5-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrazole

2,5-Dimethyl-3,4-bis-(2,4,6-trimethyl-benzoyl)-furan

1-(2,4,6-trimethyl-phenyl)-butane-1,2,3-trione-2-oxime

1-Triaethylsilyl-6-mesityl-hexa-1,3,5-triin

Refernces

• 1、 Keppler,Diez,Seifried. "Antitumor activity of phenyl substituted dihalogenobis (1-phenyl-1,3-butanedionato)titanium (IV) compounds". . p. 1832 - 1836. Retrieved 2007/10/02.