Ethyl 2-methoxy-6-methylbenzoate

Base Information

• Chemical Name: Ethyl 2-methoxy-6-methylbenzoate
• CAS No.: 6520-83-8
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Hs Code.: 29189900
• European Community (EC) Number: 613-756-7
• DSSTox Substance ID: DTXSID80343629
• Nikkaji Number: J314.932C
• Wikidata: Q72475725
• Mol file: 6520-83-8.mol

Synonyms:Ethyl 2-methoxy-6-methylbenzoate;6520-83-8;2-Methoxy-6-methylbenzoic Acid Ethyl Ester;Benzoic acid, 2-methoxy-6-methyl-, ethyl ester;MFCD00191666;2-Methoxy-6-methyl-benzoic acid ethyl ester;2-Methyl-6-methoxybenzoic acid ethyl ester;2-METHOXY-6-METHYLBENZOICACIDETHYLESTER;SCHEMBL282595;Ethyl2-methoxy-6-methylbenzoate;DTXSID80343629;ethyl 6-methyl-2-methoxybenzoate;Ethyl-2-methoxy-6-methylbenzoate;ethyl-2-methoxy-6-methyl-benzoate;AMY14522;Ethyl 2-methoxy-6-methylbenzoate #;AKOS000297427;Ethyl 2-methyl-6-(methyloxy)benzoate;AS-18474;SY043356;2-Methoxy-6-methyl benzoic acid ethyl ester;BB 0244702;CS-0036754;FT-0693311;M1120;A867709

Chemical Property of Ethyl 2-methoxy-6-methylbenzoate

Chemical Property:

• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.5
• Boiling Point: 274.076 °C at 760 mmHg
• Flash Point: 109.643 °C
• PSA: 35.53000
• Density: 1.055 g/cm³
• LogP: 2.18030
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 191

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 2-Methoxy-6-methylbenzoate ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(=O)C1=C(C=CC=C1OC)C

Technology Process of Ethyl 2-methoxy-6-methylbenzoate

There total 4 articles about Ethyl 2-methoxy-6-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 2-hydroxy-6-methylbenzoate (6555-40-4) + methyl iodide (74-88-4) → ethyl 2-methoxy-6-methylbenzoate (6520-83-8)

Guidance literature:

With potassium carbonate; In acetone; for 25h; Heating;

DOI:10.1016/S0040-4020(01)82406-6

Reference yield: 96.0%

ethyl 2-hydroxy-6-methylbenzoate (6555-40-4) + dimethyl sulfate (77-78-1) → ethyl 2-methoxy-6-methylbenzoate (6520-83-8)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1055/s-1980-29218

Reference yield:

ethyl 2-hydroxy-6-methylbenzoate (6555-40-4) → ethyl 2-methoxy-6-methylbenzoate (6520-83-8)

Guidance literature:

DOI:10.1016/S0040-4020(01)81434-4

upstream raw materials:

ethyl 2-hydroxy-6-methylbenzoate

dimethyl sulfate

methyl iodide

Downstream raw materials:

2-Methoxy-6-(2-oxo-2-phenyl-ethyl)-benzoic acid ethyl ester

ethyl ether of 2-methoxy-6-acetonylbenzoic acid

8-methoxy-3-phenyl-2-phenylsulfonyl-1-tetralone

8-methoxy-3-(4'-methoxyphenyl)-2-phenylsulfonyl-1-tetralone