1H-Indole-1-carboxamide

Base Information

Chemical Name:1H-Indole-1-carboxamide
CAS No.:13307-58-9
Molecular Formula:C9H8N2O
Molecular Weight:160.175
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30551010
Nikkaji Number:J3.262.085J
Wikidata:Q82430515
Mol file:13307-58-9.mol

Synonyms:1H-INDOLE-1-CARBOXAMIDE;13307-58-9;indole-1-carboxamide;1H-Indole-1-carboxamide(9CI);N-(carbamoyl)indole;SCHEMBL3649822;DTXSID30551010;CQILOHWHIWNQOE-UHFFFAOYSA-N

Suppliers and Price of 1H-Indole-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1H-Indole-1-carboxamide 97.00%
25G
$ 5120.00

AccelPharmtech
1H-Indole-1-carboxamide 97.00%
5G
$ 2750.00

AccelPharmtech
1H-Indole-1-carboxamide 97.00%
1G
$ 2370.00

Total 2 raw suppliers

Chemical Property of 1H-Indole-1-carboxamide

Chemical Property:

PSA：49.01000
LogP:2.08190
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:160.063662883
Heavy Atom Count:12
Complexity:193

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1H-Indole-1-carboxamide 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CN2C(=O)N

Technology Process of 1H-Indole-1-carboxamide

There total 2 articles about 1H-Indole-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1616115-84-4
N-methoxy-1H-indole-1-carboxamide

: 501-65-5
diphenyl acetylene

: 13307-58-9
indolecarboxamide

: (Z)-3-(1H-indol-2-yl)-N-methoxy-2,3-diphenylacrylamide

Guidance literature:: With [RhCl₂(p-cymene)]2; sodium acetate; In methanol; at 20 ℃; for 1h; Reagent/catalyst; Solvent; Concentration; Catalytic behavior;
DOI:10.1039/d0ob00508h

Reference yield:

: 120-72-9
indole

: 13307-58-9
indolecarboxamide

: (Z)-3-(1H-indol-2-yl)-N-methoxy-2,3-diphenylacrylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: dmap / acetonitrile / 10 h / 85 °C / Inert atmosphere

1.2: 6 h / 80 °C / Inert atmosphere

2.1: [RhCl₂(p-cymene)]2; sodium acetate / methanol / 1 h / 20 °C

With dmap; [RhCl₂(p-cymene)]2; sodium acetate; In methanol; acetonitrile;
DOI:10.1039/d0ob00508h