2-IODO-4-METHYL-6-NITROPHENOL

Base Information

• Chemical Name: 2-IODO-4-METHYL-6-NITROPHENOL
• CAS No.: 69492-91-7
• Molecular Formula: C7H6INO3
• Molecular Weight: 279.034
• Hs Code.: 2908999090
• Mol file: 69492-91-7.mol

Synonyms:2-IODO-4-METHYL-6-NITROPHENOL

Chemical Property of 2-IODO-4-METHYL-6-NITROPHENOL

Chemical Property:

• Vapor Pressure: 0.0108mmHg at 25°C
• Melting Point: 82-84°C
• Refractive Index: 1.684
• Boiling Point: 254.4°C at 760 mmHg
• PKA: 5.79±0.38(Predicted)
• Flash Point: 107.6°C
• PSA: 66.05000
• Density: 2.021g/cm³
• LogP: 2.73660

Purity/Quality:

98%min ^*data from raw suppliers

2-Iodo-4-methyl-6-nitrophenol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-IODO-4-METHYL-6-NITROPHENOL

There total 3 articles about 2-IODO-4-METHYL-6-NITROPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-methyl-2-nitrophenol (119-33-5) → 2-iodo-4-methyl-6-nitrophenol (69492-91-7)

Guidance literature:

With sodium hydrogencarbonate; N,N,N-trimethylbenzenemethanaminium dichloroiodate; In methanol; dichloromethane; for 6h; Ambient temperature;

DOI:10.1246/cl.1987.2109

Reference yield: 37.0%

p-cresol (106-44-5) → 4-methyl-2-nitrophenol (119-33-5) + 2-iodo-4-methyl-6-nitrophenol (69492-91-7)

Guidance literature:

With iodine; silver nitrate; In acetonitrile; for 2h; Ambient temperature;

Reference yield:

4-methyl-2-nitrophenol (119-33-5) + ammonia (7664-41-7) + iodine (7553-56-2,12190-71-5,8031-47-8) → 2-iodo-4-methyl-6-nitrophenol (69492-91-7)

Guidance literature:

upstream raw materials:

4-methyl-2-nitrophenol

p-cresol

ammonia

iodine

Refernces

• 1、 Gaude, Didier,Gellon, Gisele,Goaller, Raymond Le,Pierre, Jean-Louis. "Influence de la complexation sur la reactivite de nitrates d'halogenes". . p. 104 - 108. Retrieved 2007/10/02.