(2-Methoxyethoxymethyl)triethylammonium chloride

Base Information

• Chemical Name: (2-Methoxyethoxymethyl)triethylammonium chloride
• CAS No.: 60043-43-8
• Molecular Formula: C10H24ClNO2
• Molecular Weight: 225.759
• Hs Code.: 2923900090
• DSSTox Substance ID: DTXSID00553420
• Mol file: 60043-43-8.mol

Synonyms:N,N-Diethyl-N-[(2-methoxyethoxy)methyl]ethanaminium chloride;

Chemical Property of (2-Methoxyethoxymethyl)triethylammonium chloride

Chemical Property:

• Melting Point: 64 °C
• PSA: 18.46000
• LogP: -1.51260
• Water Solubility.: almost transparency in Water
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 225.1495567
• Heavy Atom Count: 14
• Complexity: 105

Purity/Quality:

98%,99%, ^*data from raw suppliers

Triethyl(2-methoxyethoxymethyl)azaniumChloride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[N+](CC)(CC)COCCOC.[Cl-]

Technology Process of (2-Methoxyethoxymethyl)triethylammonium chloride

There total 1 articles about (2-Methoxyethoxymethyl)triethylammonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-Methoxyethoxymethyl chloride (3970-21-6) + triethylamine (121-44-8) → <(2-methoxyethoxy)methyl>triethylammonium chloride (60043-43-8)

Guidance literature:

In diethyl ether;

DOI:10.1016/0040-4020(80)80089-5

Reference yield: 24.0%

7-chloro-1-heptanol (55944-70-2) + <(2-methoxyethoxy)methyl>triethylammonium chloride (60043-43-8) → triethylamine hydrochloride (554-68-7) + 7-chloro-1-(2-methoxyethoxymethoxy)heptane (77425-87-7) + bis-(7-chloroheptyloxy)methane (77425-88-8)

Guidance literature:

In acetonitrile; for 20h; Heating;

DOI:10.1039/P19810000599

Reference yield:

<(2-methoxyethoxy)methyl>triethylammonium chloride (60043-43-8) → Phosphoric acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(2-methoxy-ethoxymethoxy)-5-[3-(2-methoxy-ethoxymethyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with triethyl-amine (100190-49-6)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran / 16 h / Heating

2: 1 M tributylammonium fluoride (TBAHF) / tetrahydrofuran / 3 h / Ambient temperature

3: 95 percent / pyridine / 1 h

4: 88 percent / 8-quinolinesulfonyl chloride (QS-Cl), pyridine / 2 h / Ambient temperature

With pyridine; quinoline-8-sulfonyl chloride; tri-n-butylamine hydrofluoride; In tetrahydrofuran;

DOI:10.1021/jo00356a033

upstream raw materials:

2-Methoxyethoxymethyl chloride

triethylamine

Downstream raw materials:

triethylamine hydrochloride

7-chloro-1-(2-methoxyethoxymethoxy)heptane

bis-(7-chloroheptyloxy)methane

2-{4-Methoxy-2-[7-(2-methoxy-ethoxymethoxy)-8-methyl-non-8-en-3-ynyl]-6-trimethylsilanyl-phenyl}-4,4-dimethyl-4,5-dihydro-oxazole