Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine

Base Information

Chemical Name:Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine
CAS No.:606095-53-8
Molecular Formula:C18H17ClN2
Molecular Weight:296.799
Hs Code.:2933499090
DSSTox Substance ID:DTXSID601322679
ChEMBL ID:CHEMBL1406529
Mol file:606095-53-8.mol

Synonyms:606095-53-8;Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine;N-Benzyl-1-(2-chloro-8-methylquinolin-3-yl)methanamine;N-[(2-chloro-8-methylquinolin-3-yl)methyl]-1-phenylmethanamine;CHEMBL1406529;Oprea1_725068;MLS000718570;DTXSID601322679;HMS2668A16;3-Quinolinemethanamine,2-chloro-8-methyl-N-(phenylmethyl)-(9CI);BDBM50520044;AKOS000684358;SB71219;SMR000290838;CS-0368101;Z2049941733;3-quinolinemethanamine,2-chloro-8-methyl-n-(phenylmethyl)-

Suppliers and Price of Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine
1g
$ 378.00

Crysdot
N-Benzyl-1-(2-chloro-8-methylquinolin-3-yl)methanamine 97%
5g
$ 701.00

Chemenu
N-Benzyl-1-(2-chloro-8-methylquinolin-3-yl)methanamine 97%
5g
$ 662.00

American Custom Chemicals Corporation
BENZYL-(2-CHLORO-8-METHYL-QUINOLIN-3-YLMETHYL)-AMINE 95.00%
5MG
$ 500.56

AK Scientific
Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine
1g
$ 560.00

Total 3 raw suppliers

Chemical Property of Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine

Chemical Property:

PSA：24.92000
LogP:4.87730
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:296.1080262
Heavy Atom Count:21
Complexity:316

Purity/Quality:

98%min ^*data from raw suppliers

Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)C=C(C(=N2)Cl)CNCC3=CC=CC=C3

Technology Process of Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine

There total 4 articles about Benzyl-(2-chloro-8-methyl-quinolin-3-ylmethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 948291-50-7
2-chloro-3-(chloropmethyl)-8-methylquinoline

: 100-46-9
benzylamine

: 606095-53-8
N-benzyl-1-(2-chloro-8-methylquinolin-3-yl)methanamine

Guidance literature:: With triethylamine; In ethanol; Reflux;
DOI:10.1016/j.ejmech.2010.12.002

Reference yield:

: 73568-26-0
2-chloro-8-methyl-quinoline-3-carbaldehyde

: 606095-53-8
N-benzyl-1-(2-chloro-8-methylquinolin-3-yl)methanamine

Guidance literature:: Multi-step reaction with 3 steps

1: methanol; sodium tetrahydroborate / 0.5 h / 20 °C

2: thionyl chloride / benzene / Reflux

3: triethylamine / ethanol / Reflux

With methanol; sodium tetrahydroborate; thionyl chloride; triethylamine; In ethanol; benzene;
DOI:10.1016/j.ejmech.2010.12.002