2-Cyclohexene-1,4-diol,2-methyl-5-(1-methylethyl)-,(1S,4S,5S)-(9CI)

Base Information

• Chemical Name: 2-Cyclohexene-1,4-diol,2-methyl-5-(1-methylethyl)-,(1S,4S,5S)-(9CI)
• CAS No.: 676268-01-2
• Molecular Formula: C10H18O2
• Molecular Weight: 0
• Mol file: 676268-01-2.mol

Synonyms:2-Cyclohexene-1,4-diol,2-methyl-5-(1-methylethyl)-,(1S,4S,5S)-(9CI)

Chemical Property of 2-Cyclohexene-1,4-diol,2-methyl-5-(1-methylethyl)-,(1S,4S,5S)-(9CI)

Chemical Property:

• PSA: 40.46000
• LogP: 1.33040

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Cyclohexene-1,4-diol,2-methyl-5-(1-methylethyl)-,(1S,4S,5S)-(9CI)

There total 16 articles about 2-Cyclohexene-1,4-diol,2-methyl-5-(1-methylethyl)-,(1S,4S,5S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

(+)-(1S,4R,7R)-7-isopropyl-5-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene (114612-54-3) → (3S:4R:6R)-p-menthene-(1)-diol-(3.6) (4031-54-3,676268-01-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1016/S0031-9422(96)00863-1

Reference yield: 39.0%

(+)-(1R,4S,7R)-7-isopropyl-5-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene (114612-55-4) → (3R,4R,6S)-3,6-dihydroxymenth-1-ene (4031-53-2,4031-54-3,4031-56-5,17699-07-9,38301-95-0,61664-34-4,78037-71-5,143562-45-2,4031-55-4,676268-01-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1016/S0031-9422(96)00863-1

Reference yield: 37.0%

(-)-(3S,4S,6R)-3,6-dihydroxy-1-menthene 3-O-β-D-glucopyranoside → D-glucose (50-99-7) + 1α,6β-dihydroxy-4α-p-menth-2-ene (135502-17-9) + (+)-3S,4S,6R-3,6-dihydroxy-p-menth-1-ene (38301-95-0,676268-01-2) + (+)-Δ5-dehydro-1-hydroxyisocarvomenthol

Guidance literature:

With hydrogenchloride; In water; at 20 ℃; for 0.5h;

DOI:10.1021/acs.jnatprod.6b00491

upstream raw materials:

(R)-5-isopropyl-2-methylcyclohexa-1,3-diene

(+)-(1R,4S,7R)-7-isopropyl-5-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene

(+)-(1S,4R,7R)-7-isopropyl-5-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene

3α-hydroxycarvotagenone

Downstream raw materials:

6R-hydroxymenthol

6-hydroxyisomenthol

3,5-dinitro-benzoic acid-((1S)-isocarvomenthyl ester)

trans-(1S,5R)-5-isopropyl-2-methyl-2-cyclohexen-1-ol