Trimethylsilyl 3,3-dimethylbutanoate

Base Information

• Chemical Name: Trimethylsilyl 3,3-dimethylbutanoate
• CAS No.: 61333-82-2
• Molecular Formula: C9H20O2Si
• Molecular Weight: 188.34
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID00369942
• Wikidata: Q82157231
• Mol file: 61333-82-2.mol

Synonyms:Trimethylsilyl 3,3-dimethylbutanoate;TRIMETHYLSILYL TERT-BUTYLACETATE;61333-82-2;DTXSID00369942

Chemical Property of Trimethylsilyl 3,3-dimethylbutanoate

Chemical Property:

• Boiling Point: 54 °C (12 mmHg)
• PSA: 26.30000
• LogP: 2.80070
• Storage Temp.: 0-6°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 188.123256411
• Heavy Atom Count: 12
• Complexity: 162

Purity/Quality:

98%Min ^*data from raw suppliers

TRIMETHYLSILYL TERT-BUTYLACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)CC(=O)O[Si](C)(C)C

Technology Process of Trimethylsilyl 3,3-dimethylbutanoate

There total 2 articles about Trimethylsilyl 3,3-dimethylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

chloro-trimethyl-silane (75-77-4) + tert-Butylacetic acid (1070-83-3) → trimethylsilyl 3,3-dimethylbutanoate (61333-82-2)

Guidance literature:

tert-Butylacetic acid; With pyridine; In tetrahydrofuran; at 0 ℃; for 0.5h;

chloro-trimethyl-silane; With 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.tet.2007.01.026

Reference yield:

→ trimethylsilyl 3,3-dimethylbutanoate (61333-82-2)

Guidance literature:

entspr. Saeure, Trimethylchlorsilan/Pyridin;

Reference yield: 92.0%

chloro-trimethyl-silane (75-77-4) + trimethylsilyl 3,3-dimethylbutanoate (61333-82-2) → 2-(tert-butyl)-1,1-bis(trimethylsilyloxy)ethene (31469-23-5)

Guidance literature:

trimethylsilyl 3,3-dimethylbutanoate; With n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h;

DOI:10.1016/j.tet.2007.01.026

upstream raw materials:

chloro-trimethyl-silane

tert-Butylacetic acid

Downstream raw materials:

2-(tert-butyl)-1,1-bis(trimethylsilyloxy)ethene

Refernces