4-BROMO-2-CHLORO-6-NITROPHENOL

Base Information

• Chemical Name: 4-BROMO-2-CHLORO-6-NITROPHENOL
• CAS No.: 58349-01-2
• Molecular Formula: C6H3BrClNO3
• Molecular Weight: 252.452
• Hs Code.: 2908999090
• Mol file: 58349-01-2.mol

Synonyms:4-Bromo-2-chloro-6-nitrophenol;

Chemical Property of 4-BROMO-2-CHLORO-6-NITROPHENOL

Chemical Property:

• Vapor Pressure: 0.00929mmHg at 25°C
• Refractive Index: 1.661
• Boiling Point: 257 °C at 760 mmHg
• Flash Point: 109.2 °C
• PSA: 66.05000
• Density: 1.974 g/cm³
• LogP: 3.23950

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2-chloro-6-nitrophenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-BROMO-2-CHLORO-6-NITROPHENOL

There total 12 articles about 4-BROMO-2-CHLORO-6-NITROPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-chloro-6-nitrophenol (603-86-1) → 4-bromo-6-chloro-2-nitrophenol (58349-01-2)

Guidance literature:

With 1,2-ethanediylbis(triphenylphosphonium) ditribromide; In methanol; dichloromethane; at 20 ℃; for 0.0833333h; Solvent; regioselective reaction;

DOI:10.1007/s13738-016-0919-6

Reference yield: 88.0%

4-bromo-2-chlorophenol (3964-56-5) → 4-bromo-6-chloro-2-nitrophenol (58349-01-2)

Guidance literature:

With sulfuric acid; nitric acid; sodium nitrite; In water; propionic acid; at 30 ℃; for 3.166h; Product distribution / selectivity;

Reference yield:

4-bromo-2-chlorophenol (3964-56-5) → 2-chloro-4-nitrophenol (619-08-9) + 4-bromo-6-chloro-2-nitrophenol (58349-01-2)

Guidance literature:

With acetic acid; sodium nitrite;

DOI:10.1021/ja01332a059

upstream raw materials:

4-bromo-2-nitrophenol

4-bromo-2-chlorophenol

2,4-dibromo-6-chlorophenol

nitric acid

Downstream raw materials:

tribromo-chloro-[1,4]benzoquinone

2-chloro-4,6-dinitro-phenol

2-bromo-6-chloro-4-nitrophenol

2-bromo-5-chloro-3,6-dihydroxy-[1,4]benzoquinone