1-[(4-Methoxyphenyl)methyl]pyrrolidin-3-amine

Base Information

Chemical Name:1-[(4-Methoxyphenyl)methyl]pyrrolidin-3-amine
CAS No.:61695-08-7
Molecular Formula:C12H18N2O
Molecular Weight:279.206
Hs Code.:2933990090
Mol file:61695-08-7.mol

Synonyms:1-[(4-methoxyphenyl)methyl]pyrrolidin-3-amine;SCHEMBL11452801;MFCD09026523;AKOS009457235;F1908-2359

Suppliers and Price of 1-[(4-Methoxyphenyl)methyl]pyrrolidin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-METHOXY-BENZYL)-PYRROLIDIN-3-YLAMINE DIHYDROCHLORIDE 95.00%
5MG
$ 498.07

Total 5 raw suppliers

Chemical Property of 1-[(4-Methoxyphenyl)methyl]pyrrolidin-3-amine

Chemical Property:

PSA：38.49000
LogP:3.47040
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:206.141913202
Heavy Atom Count:15
Complexity:190

Purity/Quality:

99% ^*data from raw suppliers

1-(4-METHOXY-BENZYL)-PYRROLIDIN-3-YLAMINE DIHYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN2CCC(C2)N

Technology Process of 1-[(4-Methoxyphenyl)methyl]pyrrolidin-3-amine

There total 2 articles about 1-[(4-Methoxyphenyl)methyl]pyrrolidin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (1-(4-methoxybenzyl)pyrrolidin-3-yl)carbamate

: 61695-08-7
3-amino-1-p-methoxyphenylmethylpyrrolidine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.0c01026

Reference yield:

: 2746-25-0
p-Methoxybenzyl bromide

: 61695-08-7
3-amino-1-p-methoxyphenylmethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 40 °C

2: hydrogenchloride / 1,4-dioxane; methanol / 1 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.0c01026