4-(3-Fluorobenzoyl)piperidine

Base Information

Chemical Name:4-(3-Fluorobenzoyl)piperidine
CAS No.:639468-63-6
Molecular Formula:C12H14 F N O
Molecular Weight:207.24
Hs Code.:2933399990
DSSTox Substance ID:DTXSID80460163
Wikidata:Q82284109
Mol file:639468-63-6.mol

Synonyms:4-(3-Fluorobenzoyl)piperidine;639468-63-6;(3-Fluorophenyl)(piperidin-4-yl)methanone;(3-fluorophenyl)-piperidin-4-ylmethanone;(3-fluorophenyl)-(4-piperidyl)methanone;SCHEMBL11620780;DTXSID80460163;MFCD07368390;AKOS015920194;SB43849;CS-0454479;FT-0647227;C78376;(3-FLUOROPHENYL)-4-PIPERIDINYL-METHANONE;A834585;J-513381

Suppliers and Price of 4-(3-Fluorobenzoyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3-Fluorobenzoyl)piperidine
250mg
$ 75.00

TRC
4-(3-Fluorobenzoyl)piperidine
25mg
$ 45.00

Crysdot
(3-Fluorophenyl)(piperidin-4-yl)methanone 95+%
5g
$ 470.00

Chemenu
(3-Fluorophenyl)(piperidin-4-yl)methanone 95%
5g
$ 445.00

American Custom Chemicals Corporation
4-(3-FLUOROBENZOYL)PIPERIDINE 95.00%
5G
$ 1508.66

Acrotein
(3-Fluorophenyl)-4-piperidinyl-methanoneHCl 97%
1g
$ 185.90

Acrotein
(3-Fluorophenyl)-4-piperidinyl-methanoneHCl 97%
0.5g
$ 116.05

ACHEMBLOCK
(3-Fluorophenyl)-4-piperidinyl-methanonehydrochloride 95%
5G
$ 760.00

ACHEMBLOCK
(3-Fluorophenyl)-4-piperidinyl-methanonehydrochloride 95%
1G
$ 280.00

Total 18 raw suppliers

Chemical Property of 4-(3-Fluorobenzoyl)piperidine

Chemical Property:

Vapor Pressure:0.00038mmHg at 25°C
Refractive Index:1.522
Boiling Point:317.6°C at 760 mmHg
PKA:9.67±0.10(Predicted)
Flash Point:145.9°C
Density:1.128g/cm³
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:207.105942232
Heavy Atom Count:15
Complexity:226

Purity/Quality:

97% ^*data from raw suppliers

4-(3-Fluorobenzoyl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(=O)C2=CC(=CC=C2)F

Technology Process of 4-(3-Fluorobenzoyl)piperidine

There total 4 articles about 4-(3-Fluorobenzoyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 269741-29-9
4-(3-fluorobenzoyl)piperidine-1-carboxylic acid tert-butyl ester

: 639468-63-6
(3-fluorophenyl)(piperidin-4-yl)methanone

Guidance literature:: With hydrogenchloride; In methanol; for 2h; Heating;
DOI:10.1021/jm0309349

Reference yield:

: 4395-98-6
4-cyanopiperidine

: 639468-63-6
(3-fluorophenyl)(piperidin-4-yl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 79 percent / NaHCO₃ / 20 h / 20 °C

2.1: Mg; I₂ / diethyl ether / 1.5 h / Heating

2.2: diethyl ether / 3 h / Heating

3.1: aq.HCl / methanol / 2 h / Heating

With hydrogenchloride; iodine; sodium hydrogencarbonate; magnesium; In methanol; diethyl ether;
DOI:10.1021/jm0309349

Reference yield:

: 39546-32-2
4-carboxamidopiperidine

: 639468-63-6
(3-fluorophenyl)(piperidin-4-yl)methanone

Guidance literature:: Multi-step reaction with 4 steps

1.1: 86 percent / SOCl₂ / 3 h / Heating

2.1: 79 percent / NaHCO₃ / 20 h / 20 °C

3.1: Mg; I₂ / diethyl ether / 1.5 h / Heating

3.2: diethyl ether / 3 h / Heating

4.1: aq.HCl / methanol / 2 h / Heating

With hydrogenchloride; thionyl chloride; iodine; sodium hydrogencarbonate; magnesium; In methanol; diethyl ether;
DOI:10.1021/jm0309349