N-propylpiperazine-2-carboxamide

Base Information

Chemical Name:N-propylpiperazine-2-carboxamide
CAS No.:646523-34-4
Molecular Formula:C₈H₁₇N₃O
Molecular Weight:171.242
Hs Code.:
DSSTox Substance ID:DTXSID20459374
Nikkaji Number:J1.921.805H
Mol file:646523-34-4.mol

Synonyms:N-propylpiperazine-2-carboxamide;646523-34-4;2-Piperazinecarboxamide,N-propyl-;2-Piperazinecarboxamide,N-propyl-(9CI);SCHEMBL6626467;DTXSID20459374;AKOS012402823

Suppliers and Price of N-propylpiperazine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-propylpiperazine-2-carboxamide

Chemical Property:

PSA：53.16000
LogP:0.12250
XLogP3:-0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:171.137162174
Heavy Atom Count:12
Complexity:149

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCNC(=O)C1CNCCN1

Technology Process of N-propylpiperazine-2-carboxamide

There total 4 articles about N-propylpiperazine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 646523-38-8
1,4-dibenzyl-piperazine-2-carboxylic acid propylamide

: 646523-34-4
piperazine-2-carboxylic acid propylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃;
DOI:10.1039/b303952h DOI:10.1039/b413173h

Reference yield:

: 72351-59-8
ethyl 1,4-dibenzylpiperazin-2-carboxylate

: 646523-34-4
piperazine-2-carboxylic acid propylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: AlMe₃ / toluene / 1 h / 10 °C

1.2: 74 percent / toluene / 4 h / Heating

2.1: 96 percent / H₂ / Pd/C / ethanol / 20 °C

With hydrogen; trimethylaluminum; palladium on activated charcoal; In ethanol; toluene;
DOI:10.1039/b413173h

Reference yield:

: 111760-58-8
1,4-dibenzyl-2-hexoxymethyl-piperazine

: 646523-34-4
piperazine-2-carboxylic acid propylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: Al(CH₃)3 / toluene / 1 h / 0 °C

1.2: 74 percent / toluene / 4 h / Heating

2.1: 96 percent / H₂ / Pd/C / ethanol / 20 °C

With hydrogen; trimethylaluminum; palladium on activated charcoal; In ethanol; toluene;
DOI:10.1039/b303952h