3,4-Dihydroisoquinolin-7-amine

Base Information

Chemical Name:3,4-Dihydroisoquinolin-7-amine
CAS No.:62541-60-0
Molecular Formula:C9H10N2
Molecular Weight:146.19
Hs Code.:
DSSTox Substance ID:DTXSID90465341
Wikidata:Q82291194
Mol file:62541-60-0.mol

Synonyms:3,4-dihydroisoquinolin-7-amine;62541-60-0;7-AMINO-3,4-DIHYDROISOQUINOLINE;SCHEMBL7659749;7-Anino-3,4-dihydroisoquinoline;DTXSID90465341;ICDBZRYXNCPKRM-UHFFFAOYSA-N;AKOS006285772;AB44239;FT-0715207

Suppliers and Price of 3,4-Dihydroisoquinolin-7-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,4-DIHYDRO ISOQUINOLIN-7-AMINE 95.00%
5MG
$ 495.33

AccelPharmtech
3,4-dihydro-7-Isoquinolinamine 97.00%
25G
$ 13300.00

AccelPharmtech
3,4-dihydro-7-Isoquinolinamine 97.00%
5G
$ 5360.00

AccelPharmtech
3,4-dihydro-7-Isoquinolinamine 97.00%
1G
$ 3120.00

Total 4 raw suppliers

Chemical Property of 3,4-Dihydroisoquinolin-7-amine

Chemical Property:

PSA：38.38000
LogP:1.26060
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:146.084398327
Heavy Atom Count:11
Complexity:165

Purity/Quality:

98%min ^*data from raw suppliers

3,4-DIHYDRO ISOQUINOLIN-7-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN=CC2=C1C=CC(=C2)N

Technology Process of 3,4-Dihydroisoquinolin-7-amine

There total 3 articles about 3,4-Dihydroisoquinolin-7-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 62541-59-7
7-nitro-3,4-dihydroisoquinoline

: 62541-60-0
7-amino-3,4-dihydroisoquinoline

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In ethanol; at 60 ℃; for 1h;
DOI:10.1081/SCC-120005939

Reference yield:

: 3230-65-7
3,4-dihydroisoquinoline

: 62541-60-0
7-amino-3,4-dihydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / KNO₃; H₂SO₄

2: 88 percent / tin(II) chloride dihydrate; conc. HCl / ethanol / 1 h / 60 °C

With hydrogenchloride; sulfuric acid; potassium nitrate; tin(ll) chloride; In ethanol;
DOI:10.1081/SCC-120005939

Reference yield:

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 62541-60-0
7-amino-3,4-dihydroisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: MBS; NaOH / CH₂Cl₂

2: 76 percent / KNO₃; H₂SO₄

3: 88 percent / tin(II) chloride dihydrate; conc. HCl / ethanol / 1 h / 60 °C

With hydrogenchloride; sodium hydroxide; 1-(3-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}phenyl)-1H-pyrrole-2,5-dione; sulfuric acid; potassium nitrate; tin(ll) chloride; In ethanol; dichloromethane;
DOI:10.1081/SCC-120005939