4-benzylpiperazine-1-carbonyl Chloride

Base Information

Chemical Name:4-benzylpiperazine-1-carbonyl Chloride
CAS No.:63763-66-6
Molecular Formula:C12H15ClN2O
Molecular Weight:238.717
Hs Code.:2933599090
DSSTox Substance ID:DTXSID90605669
Wikidata:Q72442718
Mol file:63763-66-6.mol

Synonyms:63763-66-6;4-benzylpiperazine-1-carbonyl Chloride;4-Benzyl-piperazine-1-carbonylchloride;4-(phenylmethyl)piperazine-1-carbonyl chloride;SCHEMBL611401;DTXSID90605669;AKOS015917689;DB-004287;4-BENZYLPIPERAZINE-1-CARBONYLCHLORIDE;4-(phenylmethyl)-1-piperazinecarbonyl chloride;A834516

Suppliers and Price of 4-benzylpiperazine-1-carbonyl Chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
4-Benzyl-piperazine-1-carbonylchloride
2 g
$ 333.00

Biosynth Carbosynth
4-Benzyl-piperazine-1-carbonylchloride
1 g
$ 191.00

Biosynth Carbosynth
4-Benzyl-piperazine-1-carbonylchloride
500 mg
$ 110.00

Biosynth Carbosynth
4-Benzyl-piperazine-1-carbonylchloride
250 mg
$ 62.50

Biosynth Carbosynth
4-Benzyl-piperazine-1-carbonylchloride
5 g
$ 666.00

American Custom Chemicals Corporation
4-BENZYL-PIPERAZINE-1-CARBONYL CHLORIDE 95.00%
1G
$ 1036.91

AK Scientific
4-Benzylpiperazine-1-carbonylChloride
5g
$ 949.00

AK Scientific
4-Benzylpiperazine-1-carbonylChloride
2g
$ 499.00

Total 9 raw suppliers

Chemical Property of 4-benzylpiperazine-1-carbonyl Chloride

Chemical Property:

Vapor Pressure:2.32E-05mmHg at 25°C
Melting Point:92 °C
Refractive Index:1.579
Boiling Point:359.8 °C at 760 mmHg
PKA:6.21±0.10(Predicted)
Flash Point:171.4 °C
PSA：23.55000
Density:1.236 g/cm³
LogP:2.03880
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:238.0872908
Heavy Atom Count:16
Complexity:233

Purity/Quality:

97% ^*data from raw suppliers

4-Benzyl-piperazine-1-carbonylchloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)C(=O)Cl

Technology Process of 4-benzylpiperazine-1-carbonyl Chloride

There total 3 articles about 4-benzylpiperazine-1-carbonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 148120-38-1
1-(phenylmethyl)-4-[(4'-methoxyphenyl)methyl]piperazine

: 63763-66-6
4-(phenylmethyl)-1-piperazine carbonyl chloride

: 824-94-2
p-methoxybenzyl chloride

Guidance literature:: In dichloromethane;
DOI:10.1021/jo0346297

Reference yield: 51.2%

: 2759-28-6
1-phenylmethylpiperazine

: 32315-10-9
bis(trichloromethyl) carbonate

: 63763-66-6
4-(phenylmethyl)-1-piperazine carbonyl chloride

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; at -10 ℃;
DOI:10.1007/s11164-012-1003-1

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 63763-66-6
4-(phenylmethyl)-1-piperazine carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / NaHB(OAc)3 / 1,2-dichloro-ethane / 20 °C

2: 53 percent / CH₂Cl₂

With sodium tris(acetoxy)borohydride; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/jo0346297