6-chloro-3,4-dihydro-2H-1,4-benzoxazine

Base Information

Chemical Name:6-chloro-3,4-dihydro-2H-1,4-benzoxazine
CAS No.:70558-11-1
Molecular Formula:C8H8ClNO
Molecular Weight:206.06916
Hs Code.:2934999090
European Community (EC) Number:871-250-3
DSSTox Substance ID:DTXSID40500872
Nikkaji Number:J2.374.990D
Wikidata:Q82352857
Mol file:70558-11-1.mol

Synonyms:70558-11-1;6-chloro-3,4-dihydro-2H-1,4-benzoxazine;6-CHLORO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE;MFCD08544339;6-chloro-3,4-dihydro-2H-benzo[1,4]oxazine;2H-1,4-Benzoxazine, 6-chloro-3,4-dihydro-;SCHEMBL304035;3-Chloro-4-methoxybenzylalcohol;DTXSID40500872;WMVHXRNLZBQWFK-UHFFFAOYSA-N;VT1094;AKOS005072477;AB45772;DD-0714;SY130738;FT-0680936;EN300-91775;A917956;J-518544;6-Chloro-3,4-dihydro-2H-1,4-benzoxazine, AldrichCPR;Z1198179941

Suppliers and Price of 6-chloro-3,4-dihydro-2H-1,4-benzoxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-chloro-3,4-dihydro-2H-1,4-benzoxazine
50mg
$ 45.00

Sigma-Aldrich
6-chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine AldrichCPR
1g
$ 223.00

Matrix Scientific
6-Chloro-3,4-dihydro-2H-1,4-benzoxazine >95%
500mg
$ 266.00

Matrix Scientific
6-Chloro-3,4-dihydro-2H-1,4-benzoxazine >95%
1g
$ 409.00

Crysdot
6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine 95+%
1g
$ 277.00

Chemcia Scientific
6-Chloro-3,4-dihydro-2H-benzo[1,4]oxazine ＞95%
2.5 G
$ 595.00

Biosynth Carbosynth
6-Chloro-3,4-dihydro-2h-1,4-benzoxazine
100 mg
$ 113.00

Biosynth Carbosynth
6-Chloro-3,4-dihydro-2h-1,4-benzoxazine
250 mg
$ 197.50

Biosynth Carbosynth
6-Chloro-3,4-dihydro-2h-1,4-benzoxazine
500 mg
$ 315.00

Biosynth Carbosynth
6-Chloro-3,4-dihydro-2h-1,4-benzoxazine
1 g
$ 507.50

Total 20 raw suppliers

Chemical Property of 6-chloro-3,4-dihydro-2H-1,4-benzoxazine

Chemical Property:

Melting Point:33-34 °C(Solv: cyclohexane (110-82-7))
Boiling Point:104-106 °C(Press: 0.004 Torr)
PKA:3.63±0.20(Predicted)
PSA：21.26000
Density:1.253±0.06 g/cm3(Predicted)
LogP:2.28230
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:169.0294416
Heavy Atom Count:11
Complexity:142

Purity/Quality:

97% ^*data from raw suppliers

6-chloro-3,4-dihydro-2H-1,4-benzoxazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(N1)C=C(C=C2)Cl

Technology Process of 6-chloro-3,4-dihydro-2H-1,4-benzoxazine

There total 7 articles about 6-chloro-3,4-dihydro-2H-1,4-benzoxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 95-85-2
2-hydroxy-5-chloro-aniline

: 247129-85-7
(2-bromoethyl)(diphenyl)sulfonium trifluoromethanesulfonate

: 70558-11-1
6-chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: 2-hydroxy-5-chloro-aniline; With sodium hydride; In dichloromethane; at 0 ℃; for 0.0833333h; Inert atmosphere;

(2-bromoethyl)(diphenyl)sulfonium trifluoromethanesulfonate; In dichloromethane; at 25 - 30 ℃; for 15h; Inert atmosphere;