6-Nitro-1-benzofuran-2-carboxylic acid

Base Information

• Chemical Name: 6-Nitro-1-benzofuran-2-carboxylic acid
• CAS No.: 64209-68-3
• Molecular Formula: C9H5 N O5
• Molecular Weight: 207.142
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID40525989
• Wikidata: Q82394049
• Mol file: 64209-68-3.mol

Synonyms:64209-68-3;6-Nitro-1-benzofuran-2-carboxylic acid;6-nitrobenzofuran-2-carboxylic acid;6-NITRO-2-BENZOFURANCARBOXYLICACID;6-Nitro-2-benzofurancarboxylic acid;2-Benzofurancarboxylic acid, 6-nitro-;6-Nitro-1-benzo[b]furan-2-carboxylic acid;SCHEMBL1091343;DTXSID40525989;KROYLRGNLSKXHM-UHFFFAOYSA-N;AS-78461;D95507

Chemical Property of 6-Nitro-1-benzofuran-2-carboxylic acid

Chemical Property:

• PSA: 96.26000
• LogP: 2.56240
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 207.01677226
• Heavy Atom Count: 15
• Complexity: 287

Purity/Quality:

98% ^*data from raw suppliers

6-NITRO-2-BENZOFURANCARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1[N+](=O)[O-])OC(=C2)C(=O)O

Technology Process of 6-Nitro-1-benzofuran-2-carboxylic acid

There total 7 articles about 6-Nitro-1-benzofuran-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

6-nitrobenzofuran-2-carboxylic acid ethyl ester (69603-99-2) → 6-nitro-1-benzofuran-2-carboxylic acid (64209-68-3)

Guidance literature:

With potassium hydroxide; ethanol; for 1.5h; Heating / reflux;

Reference yield: 33.0%

Benzofuran-2-carboxylic acid (496-41-3) → 2-nitro-benzofuran (33094-66-5) + 6-nitro-1-benzofuran-2-carboxylic acid (64209-68-3) + 5-nitrobenzofuran-2-carboxylic acid (10242-12-3)

Guidance literature:

With nitric acid; tin(IV) chloride; In dichloromethane; at 0 ℃; for 2h;

Reference yield: 18.2%

2-hydroxy-4-nitrobenzaldehyde (2460-58-4) + methyl chloroacetate (96-34-4) → 6-nitro-1-benzofuran-2-carboxylic acid (64209-68-3)

Guidance literature:

2-hydroxy-4-nitrobenzaldehyde; methyl chloroacetate; With tetra-(n-butyl)ammonium iodide; potassium carbonate; at 130 ℃; for 12h;

With potassium hydroxide; water; In tetrahydrofuran; at 0 - 20 ℃; for 20h;

With hydrogenchloride; water; In tetrahydrofuran; pH=1;

upstream raw materials:

2-hydroxy-4-nitrobenzaldehyde

Diethyl 2-bromomalonate

Benzofuran-2-carboxylic acid

6-nitrobenzofuran-2-carboxylic acid ethyl ester

Downstream raw materials:

6-nitrobenzofuran

6-hydroxybenzofuran-2-carbonitrile

6-amino-2,3-dihydrobenzofuran

benzofuran-6-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 64209-68-3 2-BENZOFURANCARBOXYLIC ACID, 6-NITRO-

Send

Send

Metric Ton KG G Pound L ML

Send

Send