1,3-Dichloro-2-(methoxymethoxy)propane

Base Information

• Chemical Name: 1,3-Dichloro-2-(methoxymethoxy)propane
• CAS No.: 70905-45-2
• Molecular Formula: C5H10Cl2O2
• Molecular Weight: 173.039
• Hs Code.: 2909199090
• European Community (EC) Number: 679-625-1
• DSSTox Substance ID: DTXSID50415842
• Nikkaji Number: J254.936K
• Wikidata: Q82224869
• Mol file: 70905-45-2.mol

Synonyms:1,3-dichloro-2-(methoxymethoxy)propane;70905-45-2;1-Chloro-2-(chloromethyl)-3,5-dioxahexane;1,1-Bis(chloromethyl)-2,4-dioxapentane;2-chloro-1-(chloromethyl)ethyl methoxymethyl ether;SCHEMBL4474902;DTXSID50415842;GEGJQMIXBNYSQG-UHFFFAOYSA-N;MFCD00130114;AKOS027320549;AS-63628;C1197;FT-0666585;FT-0666586;D89367;EN300-170259;1,3-DICHLORO-2-(METHOXYMETHOXY)-PROPANE;Naphthalen-1-ylcarbamoylphosphoramidic dichloride;InChI=1/C5H10Cl2O2/c1-8-4-9-5(2-6)3-7/h5H,2-4H2,1H

Chemical Property of 1,3-Dichloro-2-(methoxymethoxy)propane

Chemical Property:

• Vapor Pressure: 0.556mmHg at 25°C
• Refractive Index: 1.435
• Boiling Point: 95 °C / 30mmHg
• Flash Point: 71.3°C
• PSA: 18.46000
• Density: 1,23 g/cm3
• LogP: 1.45310
• Solubility.: Chloroform, Dichloromethane
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 172.0057849
• Heavy Atom Count: 9
• Complexity: 56.9

Purity/Quality:

97% ^*data from raw suppliers

1,3-Dichloro-2-(methoxymethoxy)propane ^*data from reagent suppliers

Safty Information:

• Statements: 10-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCOC(CCl)CCl
• Uses: 1,3-Dichloro-2-(methoxymethoxy)propane (cas# 70905-45-2) is a compound useful in organic synthesis.

Technology Process of 1,3-Dichloro-2-(methoxymethoxy)propane

There total 3 articles about 1,3-Dichloro-2-(methoxymethoxy)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Dimethoxymethane (109-87-5) + 1,3-Dichloro-2-propanol (96-23-1) → 1,3-dichloro-2-(methoxymethoxy)propane (70905-45-2)

Guidance literature:

With phosphorus pentoxide; In dichloromethane;

Reference yield: 98.2%

methanol (67-56-1) + 2-(chloromethoxy)-1,3-dichloropropane (53883-86-6) → 1,3-dichloro-2-(methoxymethoxy)propane (70905-45-2)

Guidance literature:

With sodium; In tetrahydrofuran; at -78 - 20 ℃; for 12h;

DOI:10.1021/jo980094j

Reference yield: 93.0%

chloromethyl methyl ether (107-30-2) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1,3-dichloro-2-(methoxymethoxy)propane (70905-45-2)

Guidance literature:

With cetyltrimethylammonium chloride; at 30 ℃; for 20h;

DOI:10.1021/jf00044a031

upstream raw materials:

chloromethyl methyl ether

epichlorohydrin

methanol

2-(chloromethoxy)-1,3-dichloropropane

Downstream raw materials:

Dimethoxymethane

bis-(β,β'-dichloro-isopropoxy)-methane

1-(4-chlorophenyl)-3-(methoxymethoxy)cyclobutanecarbonitrile

1-phenoxy-2-methylene-3,5-dioxahexane