Benzenamine,4-(dimethylsilyl)-N,N-dimethyl-

Base Information

• Chemical Name: Benzenamine,4-(dimethylsilyl)-N,N-dimethyl-
• CAS No.: 2516-75-8
• Molecular Formula: C10H17 N Si
• Molecular Weight: 179.337
• DSSTox Substance ID: DTXSID00948019
• Mol file: 2516-75-8.mol

Synonyms:Benzenamine,4-(dimethylsilyl)-N,N-dimethyl-;SCHEMBL6215886;DTXSID00948019;4-(dimethylsilyl)-N,N-dimethylaniline

Chemical Property of Benzenamine,4-(dimethylsilyl)-N,N-dimethyl-

Chemical Property:

• Vapor Pressure: 0.0175mmHg at 25°C
• Boiling Point: 254.2°C at 760 mmHg
• Flash Point: 107.5°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 178.105201049
• Heavy Atom Count: 12
• Complexity: 126

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)[Si](C)C

Technology Process of Benzenamine,4-(dimethylsilyl)-N,N-dimethyl-

There total 5 articles about Benzenamine,4-(dimethylsilyl)-N,N-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

dimethylmonochlorosilane (1066-35-9) + 4-bromo-N,N-dimethylaniline (586-77-6) → <4-(N,N-dimethylamino)phenyl>dimethylsilane (2516-75-8)

Guidance literature:

Product distribution / selectivity; Electrochemical reaction;

Reference yield:

dimethylmonochlorosilane (1066-35-9) + 4-Iodo-N,N-dimethylaniline (698-70-4) → <4-(N,N-dimethylamino)phenyl>dimethylsilane (2516-75-8)

Guidance literature:

4-Iodo-N,N-dimethylaniline; With isopropylmagnesium chloride; In tetrahydrofuran; at -78 ℃; for 0.5h;

dimethylmonochlorosilane; In tetrahydrofuran; for 4h;

DOI:10.1039/c7cc08210j

Reference yield:

chlorodimethyl(4-dimethylaminophenyl)silane (2372-34-1) → <4-(N,N-dimethylamino)phenyl>dimethylsilane (2516-75-8)

Guidance literature:

With lithium aluminium tetrahydride;

upstream raw materials:

chlorodimethyl(4-dimethylaminophenyl)silane

dimethylmonochlorosilane

4-bromo-N,N-dimethylaniline

4-Iodo-N,N-dimethylaniline

Downstream raw materials:

1-(dimethylamino)-4-(2-methylprop-2-en-1-yl)benzene

(Z)-4-methyl-4-tert-butyl-3-[(dimethyl-p-dimethylaminophenylsilyl)methylene]-3-(p-tosyl)-1-azetidin-2-one

N,N-dimethyl-aniline

(4-(dimethylamino)phenyl)dimethylsilanol

Refernces

• 1、 Denmark, Scott E.,Smith, Russell C.,Chang, Wen-Tau T.,Muhuhi, Joseck M.. "Cross-coupling reactions of aromatic and heteroaromatic silanolates with aromatic and heteroaromatic halides". scheme or table. p. 3104 - 3118. Retrieved 2009/08/07.
• 2、 Hevesi, Laszlo,Dehon, Michael,Crutzen, Raphael,Lazarescu-Grigore, Adriana. "Kinetic Control in the Cleavage of Unsymmetrical Disilanes". . p. 2011 - 2017. Retrieved 2007/10/03.