2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID

Base Information

Chemical Name:2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID
CAS No.:503309-10-2
Molecular Formula:C7H5 B F4 O3
Molecular Weight:223.92
Hs Code.:2931900090
Mol file:503309-10-2.mol

Synonyms:Boronicacid, [2-fluoro-4-(trifluoromethoxy)phenyl]- (9CI);(2-Fluoro-4-trifluoromethoxyphenyl)boronic acid;2-Fluoro-4-trifluoromethoxybenzeneboronic acid

Suppliers and Price of 2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Fluoro-4-trifluoromethoxyphenyl Boronic Acid
100mg
$ 475.00

TRC
2-Fluoro-4-trifluoromethoxyphenylboronicAcid
500mg
$ 455.00

SynQuest Laboratories
2-Fluoro-4-trifluoromethoxybenzeneboronic acid 98%
1 g
$ 495.00

SynQuest Laboratories
2-Fluoro-4-trifluoromethoxybenzeneboronic acid 98%
250 mg
$ 295.00

Crysdot
(2-Fluoro-4-(trifluoromethoxy)phenyl)boronicacid 95+%
1g
$ 313.00

American Custom Chemicals Corporation
2-FLUORO-4-TRIFLUOROMETHOXYPHENYLBORONIC ACID 95.00%
1G
$ 537.60

AK Scientific
2-Fluoro-4-trifluoromethoxyphenylboronicacid
5g
$ 1384.00

Total 25 raw suppliers

Chemical Property of 2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID

Chemical Property:

Melting Point:114-116 °C(Solv: pentane (109-66-0))
Boiling Point:244.2±50.0 °C(Predicted)
PKA:8.09±0.58(Predicted)
PSA：49.69000
Density:1.48±0.1 g/cm3(Predicted)
LogP:0.40410
Storage Temp.:Room temperature.

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-4-trifluoromethoxyphenyl Boronic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Fluoro-4-trifluoromethoxyphenylboronic Acid is useful in the synthesis of novel series of 3-benzyl-1,3-oxazolidin-2-ones as a mGluR2 positive allosteric modulators.

Technology Process of 2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID

There total 2 articles about 2-FLUORO-4-TRIFLUOROMETHOXYBENZENEBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 168971-68-4
1-bromo-2-fluoro-4-(trifluoromethoxy)benzene

: 503309-10-2
(2-fluoro-4-(trifluoromethoxy)phenyl)boronic acid

Guidance literature:: 1-bromo-2-fluoro-4-(trifluoromethoxy)benzene; With n-butyllithium; Triisopropyl borate; In tetrahydrofuran; hexane; toluene; at -78 - -20 ℃; for 6.5h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; hexane; water; toluene; at -20 - 20 ℃; for 0.666667h; Inert atmosphere;
DOI:10.1021/jm101288t