Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

Base Information

Chemical Name:Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate
CAS No.:24562-76-3
Molecular Formula:C₁₂H₁₅NO₂
Molecular Weight:205.257
Hs Code.:2933499090
DSSTox Substance ID:DTXSID30497242
Mol file:24562-76-3.mol

Synonyms:24562-76-3;ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate;1,2,3,4-tetrahydro-quinoline-4-carboxylic acid ethyl ester;ethyl1,2,3,4-tetrahydroquinoline-4-carboxylate;DTXSID30497242;AKOS015910016;ethyl 1,2,3,4-tetrahydrocinchoninate;FT-0645623;EN300-156714;A817367;Z1463084072

Suppliers and Price of Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ethyl1,2,3,4-tetrahydroquinoline-4-carboxylate
100mg
$ 285.00

Crysdot
Ethyl1,2,3,4-tetrahydroquinoline-4-carboxylate 95+%
1g
$ 762.00

American Custom Chemicals Corporation
1,2,3,4-TETRAHYDRO-QUINOLINE-4-CARBOXYLIC ACID ETHYL ESTER 95.00%
1G
$ 994.46

Alichem
Ethyl1,2,3,4-tetrahydroquinoline-4-carboxylate
1g
$ 613.80

Total 13 raw suppliers

Chemical Property of Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

Chemical Property:

Boiling Point:307.5 °C at 760 mmHg
PKA:4.10±0.40(Predicted)
Flash Point:139.8 °C
PSA：38.33000
Density:1.101 g/cm³
LogP:2.28690
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.110278721
Heavy Atom Count:15
Complexity:230

Purity/Quality:

97% ^*data from raw suppliers

ethyl1,2,3,4-tetrahydroquinoline-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CCNC2=CC=CC=C12

Technology Process of Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

There total 4 articles about Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 13337-69-4
(RS)-1,2,3,4-tetrahydroquinoline-4-carboxylic acid

: 64-17-5
ethanol

: 24562-76-3
Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

Guidance literature:: With sulfuric acid; dihydrogen peroxide; at 120 ℃; for 0.583333h;
DOI:10.1007/BF00475570

Reference yield:

: 10447-29-7
ethyl quinoline-4-carboxylate

: 24562-76-3
Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

Guidance literature:: With nickel; decalin; at 170 ℃; Hydrogenation;

Reference yield:

: 486-74-8
4-quinolinic acid

: 24562-76-3
Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / Raney alloy/10percent NaOH / 1 h / 20 °C

2: 70 percent / H₂O₂/H₂SO₄ / 0.58 h / 120 °C

With sodium hydroxide; sulfuric acid; dihydrogen peroxide; nickel;
DOI:10.1007/BF00475570